A Human Amniotic Membrane Plug to Manage High Myopic Macular Hole Associated with Retinal Detachment

Overview

Journal Acta Ophthalmol

Specialty Ophthalmology

Date 2019 Jul 19

PMID 31318489

Citations 27

Authors

Tomaso Caporossi

Lorenzo De Angelis

Bianca Pacini

Ruggero Tartaro

Lucia Finocchio

Francesco Barca

Stanislao Rizzo

Affiliations

Soon will be listed here.

Abstract

Objective: To assess the efficacy of the human amniotic membrane (hAM) to treat (HMMH) associated with retinal detachment (RD).

Material And Methods: Ten eyes of 10 patients with recurrent HMMH and RD, who had already undergone one or more pars plana vitrectomy (PPV), underwent a PPV with an hAM plug implanted in the macular hole. The initial five patients enrolled were tamponaded with (SO) while the subsequent five patients with 10% octafluoropropane (C F ). Silicon oil was removed in all five patients 2 months later. No statistical differences were reported between the two groups.

Results: Final retinal reattachment was achieved in all the patients. BCVA improved from 1.73 logMAR to 0.94 logMAR after 6 months. No adverse events were registered during follow-up.

Conclusion: An hAM plug is an efficient substrate to manage HMMH associated with RD resulting in encouraging visual acuity recovery.

Citing Articles

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Subretinal Amniotic Membrane Transplantation in a Porcine Model of Retinal Hole.

Olufsen M, Hannibal J, Sorensen N, Christiansen A, Christensen U, Pertile G Invest Ophthalmol Vis Sci. 2024; 65(13):52.

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Human Amniotic Membrane: A Seal for Complex Retinal Detachments.

Ozdemir Zeydanli E, Ozdek S, Yalcin E, Ozdemir H Turk J Ophthalmol. 2024; 54(5):268-274.

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Safety and efficacy of human amniotic membrane plug transplantation in cases of macular hole. A scoping review.

Quiroz-Reyes M, Quiroz-Gonzalez E, Quiroz-Gonzalez M, Lima-Gomez V Int J Retina Vitreous. 2024; 10(1):82.

PMID: 39456107 PMC: 11515266. DOI: 10.1186/s40942-024-00600-1.

Outcomes of amniotic membrane transplant for refractory macular hole - an optical coherence tomography and autofluorescence long-term study.

Proenca H, Antunes M, Ferreira J, Magro P, Faria M, Marques-Neves C Graefes Arch Clin Exp Ophthalmol. 2024; 263(2):315-326.

PMID: 39311975 DOI: 10.1007/s00417-024-06609-4.