Best-Evidence Rehabilitation for Chronic Pain Part 2: Pain During and After Cancer Treatment

Overview

Journal J Clin Med

Specialty General Medicine

Date 2019 Jul 10

PMID 31284377

Citations 11

Authors

An De Groef

Frauke Penen

Lore Dams

Elien Van der Gucht

Jo Nijs

Mira Meeus

Affiliations

Soon will be listed here.

Abstract

Pain during, and especially after, cancer remains underestimated and undertreated. Moreover, both patients and health care providers are not aware of potential benefits of rehabilitation strategies for the management of pain during and following cancer treatment. In this paper, we firstly provided a state-of-the-art overview of the best evidence rehabilitation modalities for patients having (persistent) pain during and following cancer treatment, including educational interventions, specific exercise therapies, manual therapies, general exercise therapies and mind-body exercise therapies. Secondly, the findings were summarized from a clinical perspective and discussed from a scientific perspective. In conclusion, best evidence suggests that general exercise therapy has small pain-relieving effects. Supporting evidence for mind-body exercise therapy is available only in breast cancer patients. At this moment, there is a lack of high-quality evidence to support the use of specific exercises and manual therapy at the affected region for pain relief during and after cancer treatment. No clinically relevant results were found in favor of educational interventions restricted to a biomedical approach of pain. To increase available evidence these rehabilitation modalities should be applied according to, and within, a multidisciplinary biopsychosocial pain management approach. Larger, well-designed clinical trials tailored to the origin of pain and with proper evaluation of pain-related functioning and the patient's pain experience are needed.

Citing Articles

Effect of perceived injustice-targeted pain neuroscience education compared with biomedically focused education in breast cancer survivors: a study protocol for a multicentre randomised controlled trial (BCS-PI trial).

Roose E, Huysmans E, Leysen L, Mostaqim K, Van Wilgen P, Beckwee D BMJ Open. 2024; 14(1):e075779.

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Non-Surgical Site Pain in Women following Breast Cancer Surgery: A Systematic Review and Meta-Analysis.

Burton G, Masannat Y, Forget P Breast Care (Basel). 2023; 18(5):399-411.

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Cancer Pain Management: A Narrative Review of Current Concepts, Strategies, and Techniques.

Mestdagh F, Steyaert A, Lavandhomme P Curr Oncol. 2023; 30(7):6838-6858.

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Effects of Brain Wave Vibration Training on the Pain and Fatigue Disturbance Symptom Cluster in Persons with Cancer: A Randomized Controlled Trial.

Lee N, Kim B Healthcare (Basel). 2023; 11(7).

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The role of exercise for pain management in adults living with and beyond cancer: a systematic review and meta-analysis.

Cuthbert C, Twomey R, Bansal M, Rana B, Dhruva T, Livingston V Support Care Cancer. 2023; 31(5):254.

PMID: 37039883 PMC: 10088810. DOI: 10.1007/s00520-023-07716-4.

References

Andrykowski M, Curran S, Carpenter J, Studts J, Cunningham L, McGrath P . Rheumatoid symptoms following breast cancer treatment: a controlled comparison. J Pain Symptom Manage. 1999; 18(2):85-94. DOI: 10.1016/s0885-3924(99)00053-6. View

Fellowes D, Barnes K, Wilkinson S . Aromatherapy and massage for symptom relief in patients with cancer. Cochrane Database Syst Rev. 2004; (2):CD002287. DOI: 10.1002/14651858.CD002287.pub2. View

Dworkin R, Turk D, Farrar J, Haythornthwaite J, Jensen M, Katz N . Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2004; 113(1-2):9-19. DOI: 10.1016/j.pain.2004.09.012. View

Holland J, Reznik I . Pathways for psychosocial care of cancer survivors. Cancer. 2005; 104(11 Suppl):2624-37. DOI: 10.1002/cncr.21252. View

Beurskens C, van Uden C, Strobbe L, Oostendorp R, Wobbes T . The efficacy of physiotherapy upon shoulder function following axillary dissection in breast cancer, a randomized controlled study. BMC Cancer. 2007; 7:166. PMC: 2031897. DOI: 10.1186/1471-2407-7-166. View

Andersen L, Kjaer M, Sogaard K, Hansen L, Kryger A, Sjogaard G . Effect of two contrasting types of physical exercise on chronic neck muscle pain. Arthritis Rheum. 2008; 59(1):84-91. DOI: 10.1002/art.23256. View

Hwang J, Chang H, Shim Y, Park W, Park W, Huh S . Effects of supervised exercise therapy in patients receiving radiotherapy for breast cancer. Yonsei Med J. 2008; 49(3):443-50. PMC: 2615347. DOI: 10.3349/ymj.2008.49.3.443. View

Bennett M, Bagnall A, Closs J . How effective are patient-based educational interventions in the management of cancer pain? Systematic review and meta-analysis. Pain. 2009; 143(3):192-199. DOI: 10.1016/j.pain.2009.01.016. View

Jones L, Eves N, Haykowsky M, Freedland S, Mackey J . Exercise intolerance in cancer and the role of exercise therapy to reverse dysfunction. Lancet Oncol. 2009; 10(6):598-605. DOI: 10.1016/S1470-2045(09)70031-2. View

10.

Mehnert A . Employment and work-related issues in cancer survivors. Crit Rev Oncol Hematol. 2010; 77(2):109-30. DOI: 10.1016/j.critrevonc.2010.01.004. View

11.

McNeely M, Campbell K, Ospina M, Rowe B, Dabbs K, Klassen T . Exercise interventions for upper-limb dysfunction due to breast cancer treatment. Cochrane Database Syst Rev. 2010; (6):CD005211. DOI: 10.1002/14651858.CD005211.pub2. View

12.

Fernandez-Lao C, Cantarero-Villanueva I, Fernandez-de-Las-Penas C, Del-Moral-Avila R, Menjon-Beltran S, Arroyo-Morales M . Widespread mechanical pain hypersensitivity as a sign of central sensitization after breast cancer surgery: comparison between mastectomy and lumpectomy. Pain Med. 2010; 12(1):72-8. DOI: 10.1111/j.1526-4637.2010.01027.x. View

13.

Smart K, Blake C, Staines A, Doody C . The Discriminative validity of "nociceptive," "peripheral neuropathic," and "central sensitization" as mechanisms-based classifications of musculoskeletal pain. Clin J Pain. 2011; 27(8):655-63. DOI: 10.1097/AJP.0b013e318215f16a. View

14.

Ling C, Lui L, So W . Do educational interventions improve cancer patients' quality of life and reduce pain intensity? Quantitative systematic review. J Adv Nurs. 2011; 68(3):511-20. DOI: 10.1111/j.1365-2648.2011.05841.x. View

15.

Stout N, Binkley J, Schmitz K, Andrews K, Hayes S, Campbell K . A prospective surveillance model for rehabilitation for women with breast cancer. Cancer. 2012; 118(8 Suppl):2191-200. DOI: 10.1002/cncr.27476. View

16.

Carvalho A, Vital F, Soares B . Exercise interventions for shoulder dysfunction in patients treated for head and neck cancer. Cochrane Database Syst Rev. 2012; (4):CD008693. PMC: 11537249. DOI: 10.1002/14651858.CD008693.pub2. View

17.

Rock C, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya K, Schwartz A . Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin. 2012; 62(4):243-74. DOI: 10.3322/caac.21142. View

18.

Koller A, Miaskowski C, de Geest S, Opitz O, Spichiger E . A systematic evaluation of content, structure, and efficacy of interventions to improve patients' self-management of cancer pain. J Pain Symptom Manage. 2012; 44(2):264-84. DOI: 10.1016/j.jpainsymman.2011.08.015. View

19.

Mishra S, Scherer R, Geigle P, Berlanstein D, Topaloglu O, Gotay C . Exercise interventions on health-related quality of life for cancer survivors. Cochrane Database Syst Rev. 2012; (8):CD007566. PMC: 7387117. DOI: 10.1002/14651858.CD007566.pub2. View

20.

Mishra S, Scherer R, Snyder C, Geigle P, Berlanstein D, Topaloglu O . Exercise interventions on health-related quality of life for people with cancer during active treatment. Cochrane Database Syst Rev. 2012; (8):CD008465. PMC: 7389071. DOI: 10.1002/14651858.CD008465.pub2. View