Electrospun Sesbania Gum-Based Polymeric -Halamines for Antibacterial Applications

Overview

Journal Polymers (Basel)

Publisher MDPI

Date 2019 Jul 4

PMID 31266230

Citations 2

Authors

Shi Lan

Yaning Lu

Jinghua Zhang

Yanan Guo

Chun Li

Shuang Zhao

Xianliang Sheng

Alideertu Dong

Affiliations

Soon will be listed here.

Abstract

Microorganism pollution induced by pathogens has become a serious concern in recent years. In response, research on antibacterial -halamines has made impressive progress in developing ways to combat this pollution. While synthetic polymer-based -halamines have been widely developed and in some cases even commercialized, -halamines based on naturally occurring polymers remain underexplored. In this contribution, we report for the first time on a strategy for developing sesbania gum (SG)-based polymeric -halamines by a four-step approach Using SG as the initial polymer, we obtained SG-based polymeric -halamines (abbreviated as cSG-PAN nanofibers) via a step-by-step controllable synthesis process. With the assistance of advanced techniques, the as-synthesized cSG-PAN nanofibers were systematically characterized in terms of their chemical composition and morphology. In a series of antibacterial and cytotoxicity evaluations, the as-obtained cSG-PAN nanofibers displayed good antibacterial activity against and , as well as low cytotoxicity towards A549 cells. We believe this study offers a guide for developing naturally occurring polymer-based antibacterial -halamines that have great potential for antibacterial applications.

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