: an Emerging Pathogen in Humans

Overview

Journal Emerg Microbes Infect

Specialty Infectious Diseases

Date 2019 Jul 2

PMID 31259664

Citations 98

Authors

Nadia Rodriguez-Medina

Humberto Barrios-Camacho

Josefina Duran-Bedolla

Ulises Garza-Ramos

Affiliations

Soon will be listed here.

Abstract

The complex comprises seven related species, including . is a versatile bacterium capable of colonizing different hosts such as plants, humans, insects and animals. Currently, is gaining recognition as a cause of several human infections; nevertheless, its virulence profile is not fully characterized. The clinical significance of infection is hidden by imprecise detection methods that underestimate its real prevalence; however, several methods have been developed to correctly identify this species. Recent studies of carbapenemase-producing and colistin-resistant strains demonstrate a potential reservoir of multidrug-resistant genes. This finding presents an imminent scenario for spreading antimicrobial resistant genes among close relatives and, more concerningly, in clinical and environmental settings. Since was identified as a novel bacterial species, different research groups have contributed findings elucidating this pathogen; however, important details about its epidemiology, pathogenesis and ecology are still missing. This review highlights the most significant aspects of , discussing its different phenotypes, mechanisms of resistance, and virulence traits, as well as the types of infections associated with this pathogen.

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