On the Neuromodulatory Pathways of the Brain by Means of Transcranial Focused Ultrasound

Overview

Journal Curr Opin Biomed Eng

Specialty Biomedical Engineering

Date 2019 Jun 22

PMID 31223668

Citations 18

Authors

Xiaodan Niu

Kai Yu

Bin He

Affiliations

Soon will be listed here.

Abstract

For last decade, low-intensity transcranial focused ultrasound (tFUS) has been rapidly developed for a myriad of successful applications in neuromodulation. tFUS possesses high spatial resolution, focality and depth penetration as a noninvasive neuromodulation tool. Despite the promise, confounding activation can be observed in rodents when stimulation parameters are not selected carefully. Here we summarize the existing classes of observations for ultrasound neuromodulation: ultrasound directly activates a localized area, or ultrasound indirectly activates auditory pathways, which further propagates to other cortical networks. We also present control animal studies, which suggest that underlying tFUS brain modulation is characterized by localized activation independent of auditory networks activations.

Citing Articles

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