New Tools for Recombinant Protein Production in Escherichia Coli: A 5-year Update

Overview

Journal Protein Sci

Specialty Biochemistry

Date 2019 Jun 21

PMID 31219641

Citations 113

Authors

German L Rosano

Enrique S Morales

Eduardo A Ceccarelli

Affiliations

Soon will be listed here.

Abstract

The production of proteins in sufficient amounts is key for their study or use as biotherapeutic agents. Escherichia coli is the host of choice for recombinant protein production given its fast growth, easy manipulation, and cost-effectiveness. As such, its protein production capabilities are continuously being improved. Also, the associated tools (such as plasmids and cultivation conditions) are subject of ongoing research to optimize product yield. In this work, we review the latest advances in recombinant protein production in E. coli.

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