Temporal, Plant Part, and Interpopulation Variability of Secondary Metabolites and Antioxidant Activity of L

Overview

Journal Plants (Basel)

Date 2019 Jun 20

PMID 31213017

Citations 7

Authors

Nenad Zlatic

Dragana Jakovljevic

Milan Stankovic

Affiliations

Soon will be listed here.

Abstract

Variations in abiotic environmental factors have significant effects on quantity and quality of secondary metabolites, which is particularly important for plant species that possess biologically active compounds. The purpose of this study is determination of the total phenolic content, flavonoid concentration, and antioxidant activity of the different parts of L. (Asteraceae) sampled from different populations and in different time periods. The amounts obtained for the total phenolics varied from 16.73 to 89.85 mg of gallic acid (GA)/g. The concentration of flavonoids ranged from 9.32 to 376.22 mg of rutin (Ru)/g. The IC values of antioxidant activity determined using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical method varied from 161.60 to 1563.02 μg/ml. The inflorescence and roots possessed high concentration of phenolic compounds and significant antioxidant activity, while leaves contained the highest concentration of flavonoids. Additionally, the quantity of the phenolics, as well as antioxidant activity, significantly varied among the different populations due to different impacts of environmental factors. This research showed that represents an abundant source of bioactive substances, and that the quantity of these compounds greatly differs among the different populations as well as in the same populations regarding the different time periods as well as plant parts.

Citing Articles

Functional Activity of the Antioxidant System of Genus Plants in the Republic of Buryatia (Russia) and Its Significance in Plant Adaptation.

Zhigzhitzhapova S, Dylenova E, Goncharova D, Zhigzhitzhapov B, Emelyanova E, Polonova A Plants (Basel). 2024; 13(18).

PMID: 39339609 PMC: 11435044. DOI: 10.3390/plants13182630.

Leaves from Four Congo-Brazzaville Regions: Antioxidant Capacity, Anti-Inflammatory Activity and Proportional Accumulation of Phytochemicals.

Ngoka V, Oyegue Liabagui S, Obiang C, Begouabe H, Nsonde Ntandou G, Imboumy-Limoukou R Plants (Basel). 2023; 12(18).

PMID: 37765435 PMC: 10535678. DOI: 10.3390/plants12183271.

Diverse organ-specific localisation of a chemical defence, cyanogenic glycosides, in flowers of eleven species of Proteaceae.

Ritmejeryte E, Boughton B, Bayly M, Miller R PLoS One. 2023; 18(4):e0285007.

PMID: 37104509 PMC: 10138830. DOI: 10.1371/journal.pone.0285007.

Biological Activities and Chemical Profile of and Ethanolic Extracts.

Buza V, Niculae M, Hanganu D, Pall E, Burtescu R, Olah N Molecules. 2022; 27(11).

PMID: 35684497 PMC: 9182457. DOI: 10.3390/molecules27113560.

Physiological Responses of Salinized Fenugreek ( L.) Plants to Foliar Application of Salicylic Acid.

Abdelhameed R, Abdel Latef A, Shehata R Plants (Basel). 2021; 10(4).

PMID: 33808186 PMC: 8067232. DOI: 10.3390/plants10040657.

References

Quettier-Deleu C, Gressier B, Vasseur J, Dine T, Brunet C, Luyckx M . Phenolic compounds and antioxidant activities of buckwheat (Fagopyrum esculentum Moench) hulls and flour. J Ethnopharmacol. 2000; 72(1-2):35-42. DOI: 10.1016/s0378-8741(00)00196-3. View

Zhao Y, Zhang M, Shi Q, Kiyota H . Chemical constituents of plants from the genus Inula. Chem Biodivers. 2006; 3(4):371-84. DOI: 10.1002/cbdv.200690041. View

Deriu A, Zanetti S, Sechi L, Marongiu B, Piras A, Porcedda S . Antimicrobial activity of Inula helenium L. essential oil against Gram-positive and Gram-negative bacteria and Candida spp. Int J Antimicrob Agents. 2008; 31(6):588-90. DOI: 10.1016/j.ijantimicag.2008.02.006. View

Ganzera M, Guggenberger M, Stuppner H, Zidorn C . Altitudinal variation of secondary metabolite profiles in flowering heads of Matricaria chamomilla cv. BONA. Planta Med. 2008; 74(4):453-7. DOI: 10.1055/s-2008-1034326. View

Oh M, Trick H, Rajashekar C . Secondary metabolism and antioxidants are involved in environmental adaptation and stress tolerance in lettuce. J Plant Physiol. 2008; 166(2):180-91. DOI: 10.1016/j.jplph.2008.04.015. View

Papageorgiou V, Gardeli C, Mallouchos A, Papaioannou M, Komaitis M . Variation of the chemical profile and antioxidant behavior of Rosmarinus officinalis L. and Salvia fruticosa Miller grown in Greece. J Agric Food Chem. 2008; 56(16):7254-64. DOI: 10.1021/jf800802t. View

Ksouri R, Megdiche W, Falleh H, Trabelsi N, Boulaaba M, Smaoui A . Influence of biological, environmental and technical factors on phenolic content and antioxidant activities of Tunisian halophytes. C R Biol. 2008; 331(11):865-73. DOI: 10.1016/j.crvi.2008.07.024. View

Binder B, Peebles C, Shanks J, San K . The effects of UV-B stress on the production of terpenoid indole alkaloids in Catharanthus roseus hairy roots. Biotechnol Prog. 2009; 25(3):861-5. DOI: 10.1002/btpr.97. View

Tosun M, Ercisli S, Sengul M, Ozer H, Polat T, Ozturk E . Antioxidant properties and total phenolic content of eight Salvia species from Turkey. Biol Res. 2009; 42(2):175-81. DOI: /S0716-97602009000200005. View

10.

Erturk Y, Ercisli S, Sengul M, Eser Z, Haznedar A, Turan M . Seasonal variation of total phenolic, antioxidant activity and minerals in fresh tea shoots (Camellia sinensis var. sinensis). Pak J Pharm Sci. 2010; 23(1):69-74. View

11.

Barros L, Carvalho A, Ferreira I . Comparing the composition and bioactivity of Crataegus Monogyna flowers and fruits used in folk medicine. Phytochem Anal. 2010; 22(2):181-8. DOI: 10.1002/pca.1267. View

12.

Talib W, Mahasneh A . Antiproliferative activity of plant extracts used against cancer in traditional medicine. Sci Pharm. 2010; 78(1):33-45. PMC: 3002826. DOI: 10.3797/scipharm.0912-11. View

13.

Ramakrishna A, Ravishankar G . Influence of abiotic stress signals on secondary metabolites in plants. Plant Signal Behav. 2011; 6(11):1720-31. PMC: 3329344. DOI: 10.4161/psb.6.11.17613. View

14.

Kliebenstein D, Osbourn A . Making new molecules - evolution of pathways for novel metabolites in plants. Curr Opin Plant Biol. 2012; 15(4):415-23. DOI: 10.1016/j.pbi.2012.05.005. View

15.

Wang J, Zhao Y, Guo C, Zhang S, Liu C, Zhang D . Ultrasound-assisted extraction of total flavonoids from Inula helenium. Pharmacogn Mag. 2012; 8(30):166-70. PMC: 3371440. DOI: 10.4103/0973-1296.96581. View

16.

Li Y, Ni Z, Zhu M, Dong M, Wang S, Shi Q . Antitumour activities of sesquiterpene lactones from Inula helenium and Inula japonica. Z Naturforsch C J Biosci. 2012; 67(7-8):375-80. DOI: 10.1515/znc-2012-7-804. View

17.

Park E, Kim Y, Park S, Kim H, Lee J, Lee D . Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. reduces inflammation in LPS-activated RAW 264.7 cells and CLP-induced septic mice. Food Chem Toxicol. 2013; 55:386-95. DOI: 10.1016/j.fct.2012.12.027. View

18.

Kumar S, Pandey A . Chemistry and biological activities of flavonoids: an overview. ScientificWorldJournal. 2014; 2013:162750. PMC: 3891543. DOI: 10.1155/2013/162750. View

19.

Larbat R, Paris C, Le Bot J, Adamowicz S . Phenolic characterization and variability in leaves, stems and roots of Micro-Tom and patio tomatoes, in response to nitrogen limitation. Plant Sci. 2014; 224:62-73. DOI: 10.1016/j.plantsci.2014.04.010. View

20.

Valares Masa C, Diaz T, Alias Gallego J, Chaves Lobon N . Quantitative Variation of Flavonoids and Diterpenes in Leaves and Stems of Cistus ladanifer L. at Different Ages. Molecules. 2016; 21(3):275. PMC: 6274041. DOI: 10.3390/molecules21030275. View