Bostrychines A-F, Six Novel Mycosporine-Like Amino-Acids and a Novel Betaine from the Red Alga

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2019 Jun 19

PMID 31207903

Citations 17

Authors

Maria Orfanoudaki

Anja Hartmann

Helena Miladinovic

Hieu Nguyen Ngoc

Ulf Karsten

Markus Ganzera

Affiliations

Soon will be listed here.

Abstract

Various red algae have repeatedly been reported to produce a variety of UV-absorbing mycosporine-like amino acids (MAAs), compounds that are well-known as natural sun-screens, as well as a plethora of betaines, metabolites which contribute to the osmotic balance under salt stress. Among other Rhodophyta, , which is thriving as epiphyte on salt marsh plants in Europe and hence experiences extreme environmental conditions such as desiccation, UV-stress and osmotic stress, has barely been investigated for its secondary metabolites. In the present study, seven mycosporine like-amino acids and two betaines were isolated from using various chromatographic techniques. Their structures were confirmed by Nuclear Magnetic Resonance (NMR) spectroscopy and High Resolution Mass Spectrometry (HRMS). Six MAAs and one betaine were chemically characterized as new natural products.

Citing Articles

Biotechnological Potential of Macroalgae during Seasonal Blooms for Sustainable Production of UV-Absorbing Compounds.

Rosic N, Thornber C Mar Drugs. 2023; 21(12).

PMID: 38132954 PMC: 10744652. DOI: 10.3390/md21120633.

Recent progress in unraveling the biosynthesis of natural sunscreens mycosporine-like amino acids.

Chen M, Jiang Y, Ding Y J Ind Microbiol Biotechnol. 2023; 50(1).

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Isolation and Structure Elucidation of Novel Mycosporine-like Amino Acids from the Two Intertidal Red Macroalgae and .

Orfanoudaki M, Alilou M, Hartmann A, Mayr J, Karsten U, Nguyen-Ngoc H Mar Drugs. 2023; 21(10).

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Applications of mycosporine-like amino acids beyond photoprotection.

Punchakara A, Prajapat G, Bairwa H, Jain S, Agrawal A Appl Environ Microbiol. 2023; 89(11):e0074023.

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Recent Advances and Future Prospects of Mycosporine-like Amino Acids.

Peng J, Guo F, Liu S, Fang H, Xu Z, Wang T Molecules. 2023; 28(14).

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