Nociception and the Neonatal Brain

Overview

Journal Semin Fetal Neonatal Med

Publisher Elsevier

Specialties Gynecology & Obstetrics
Pediatrics

Date 2019 Jun 16

PMID 31201139

Citations 10

Authors

Deniz Gursul

Caroline Hartley

Rebeccah Slater

Affiliations

Soon will be listed here.

Abstract

Measuring brain activity in infants provides an objective surrogate approach with which to infer pain perception following noxious events. Here we discuss different approaches which can be used to measure noxious-evoked brain activity, and discuss how these measures can be used to assess the analgesic efficacy of pharmacological and non-pharmacological interventions. We review factors that can modulate noxious-evoked brain activity, which may impact infant pain experience, including gestational age, sex, prior pain, stress, and illness.

Citing Articles

Depression of cortical neuronal activity after a low-dose fentanyl in preterm infants.

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Impact of breast milk on cortical pain response in newborns during the heel prick procedure: a randomized controlled trial.

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