How Immunoglobulin V Kappa Genes Rearrange

Overview

Journal J Immunol

Specialty Allergy & Immunology

Date 1987 Dec 1

PMID 3119721

Citations 31

Authors

M A Shapiro

M Weigert

Affiliations

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Abstract

Recombination at the immunoglobulin kappa light chain locus creates a complete variable region gene and its reciprocal product. The results presented here show that reciprocal products may be substrates for secondary recombination and that at least one V kappa group rearranges by inversion.

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