Interferon-γ As a Potential Link Between Diabetes Mellitus and Dementia

Overview

Journal J Neurosci

Specialty Neurology

Date 2019 Jun 14

PMID 31189539

Citations 4

Authors

Danielle Cozachenco

Maria C Selles

Felipe C Ribeiro

Affiliations

Soon will be listed here.

Citing Articles

Menaquinone-7 and its therapeutic potential in type 2 diabetes mellitus based on a Zucker diabetic fatty rat model.

Mrosewski I, Mantel V, Urbank M, Schulze-Tanzil G, Werner C, Gogele C Heliyon. 2024; 10(23):e40826.

PMID: 39719993 PMC: 11666950. DOI: 10.1016/j.heliyon.2024.e40826.

Transcranial photobiomodulation improves insulin therapy in diabetic microglial reactivity and the brain drainage system.

Liu S, Li D, Yu T, Zhu J, Semyachkina-Glushkovskaya O, Zhu D Commun Biol. 2023; 6(1):1239.

PMID: 38066234 PMC: 10709608. DOI: 10.1038/s42003-023-05630-3.

The extract of Sclerocarya birrea, Nauclea latifolia, and Piper longum mixture ameliorates diabetes-associated cognitive dysfunction.

Tientcheu J, Ngueguim F, Gounoue R, Mbock M, Ngapout R, Kandeda A Metab Brain Dis. 2023; 38(8):2773-2796.

PMID: 37821784 DOI: 10.1007/s11011-023-01291-7.

Differential Expression of Inflammatory Markers in Hypoglycemia Unawareness Associated with Type 1 Diabetes: A Case Report.

Al Zoubi Y, Mussa B, Srivastava A, Mohammed A, Abdelgadir E, Bashier A Brain Sci. 2020; 11(1).

PMID: 33375551 PMC: 7823509. DOI: 10.3390/brainsci11010017.

References

Kondo F, Asanuma M, Miyazaki I, Kondo Y, Tanaka K, Makino H . Progressive cortical atrophy after forebrain ischemia in diabetic rats. Neurosci Res. 2001; 39(3):339-46. DOI: 10.1016/s0168-0102(00)00233-9. View

Biessels G, Staekenborg S, Brunner E, Brayne C, Scheltens P . Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol. 2005; 5(1):64-74. DOI: 10.1016/S1474-4422(05)70284-2. View

Zuliani G, Ranzini M, Guerra G, Rossi L, Munari M, Zurlo A . Plasma cytokines profile in older subjects with late onset Alzheimer's disease or vascular dementia. J Psychiatr Res. 2006; 41(8):686-93. DOI: 10.1016/j.jpsychires.2006.02.008. View

Haynes S, Hollopeter G, Yang G, Kurpius D, Dailey M, Gan W . The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat Neurosci. 2006; 9(12):1512-9. DOI: 10.1038/nn1805. View

Zhang S, Murphy T . Imaging the impact of cortical microcirculation on synaptic structure and sensory-evoked hemodynamic responses in vivo. PLoS Biol. 2007; 5(5):e119. PMC: 1854912. DOI: 10.1371/journal.pbio.0050119. View

Seo S, Lee B, Kim E, Chin J, Cho Y, Yoon U . Clinical significance of microbleeds in subcortical vascular dementia. Stroke. 2007; 38(6):1949-51. DOI: 10.1161/STROKEAHA.106.477315. View

Damani M, Zhao L, Fontainhas A, Amaral J, Fariss R, Wong W . Age-related alterations in the dynamic behavior of microglia. Aging Cell. 2010; 10(2):263-76. PMC: 3056927. DOI: 10.1111/j.1474-9726.2010.00660.x. View

Li G, Xu X, Wang D, Wang J, Wang Y, Yu J . Microglial activation during acute cerebral infarction in the presence of diabetes mellitus. Neurol Sci. 2011; 32(6):1075-9. DOI: 10.1007/s10072-011-0632-2. View

Browne T, McQuillan K, McManus R, OReilly J, Mills K, Lynch M . IFN-γ Production by amyloid β-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease. J Immunol. 2013; 190(5):2241-51. DOI: 10.4049/jimmunol.1200947. View

10.

Ishimaru M, Tsukimoto M, Harada H, Kojima S . Involvement of P2Y₁₁ receptor in IFN-γ-induced IL-6 production in human keratinocytes. Eur J Pharmacol. 2013; 703(1-3):67-73. DOI: 10.1016/j.ejphar.2013.02.020. View

11.

Cianchetti F, Kim D, Dimiduk S, Nishimura N, Schaffer C . Stimulus-evoked calcium transients in somatosensory cortex are temporarily inhibited by a nearby microhemorrhage. PLoS One. 2013; 8(5):e65663. PMC: 3665593. DOI: 10.1371/journal.pone.0065663. View

12.

Hickman S, Kingery N, Ohsumi T, Borowsky M, Wang L, Means T . The microglial sensome revealed by direct RNA sequencing. Nat Neurosci. 2013; 16(12):1896-905. PMC: 3840123. DOI: 10.1038/nn.3554. View

13.

Hilal S, Saini M, Tan C, Catindig J, Koay W, Niessen W . Cerebral microbleeds and cognition: the epidemiology of dementia in Singapore study. Alzheimer Dis Assoc Disord. 2013; 28(2):106-12. DOI: 10.1097/WAD.0000000000000015. View

14.

Minogue A, Jones R, Kelly R, McDonald C, Connor T, Lynch M . Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice. Neurobiol Aging. 2014; 35(6):1442-52. DOI: 10.1016/j.neurobiolaging.2013.12.026. View

15.

Ninomiya T . Diabetes mellitus and dementia. Curr Diab Rep. 2014; 14(5):487. DOI: 10.1007/s11892-014-0487-z. View

16.

Gyoneva S, Davalos D, Biswas D, Swanger S, Garnier-Amblard E, Loth F . Systemic inflammation regulates microglial responses to tissue damage in vivo. Glia. 2014; 62(8):1345-60. PMC: 4408916. DOI: 10.1002/glia.22686. View

17.

Belkhelfa M, Rafa H, Medjeber O, Arroul-Lammali A, Behairi N, Abada-Bendib M . IFN-γ and TNF-α are involved during Alzheimer disease progression and correlate with nitric oxide production: a study in Algerian patients. J Interferon Cytokine Res. 2014; 34(11):839-47. DOI: 10.1089/jir.2013.0085. View

18.

Hu X, Leak R, Shi Y, Suenaga J, Gao Y, Zheng P . Microglial and macrophage polarization—new prospects for brain repair. Nat Rev Neurol. 2014; 11(1):56-64. PMC: 4395497. DOI: 10.1038/nrneurol.2014.207. View

19.

Okizaki S, Ito Y, Hosono K, Oba K, Ohkubo H, Amano H . Suppressed recruitment of alternatively activated macrophages reduces TGF-β1 and impairs wound healing in streptozotocin-induced diabetic mice. Biomed Pharmacother. 2015; 70:317-25. DOI: 10.1016/j.biopha.2014.10.020. View

20.

Jay T, Miller C, Cheng P, Graham L, Bemiller S, Broihier M . TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models. J Exp Med. 2015; 212(3):287-95. PMC: 4354365. DOI: 10.1084/jem.20142322. View