Recent Research Advances in Mitosis During Mammalian Gametogenesis

Overview

Journal Cells

Publisher MDPI

Specialties Biochemistry
Biophysics
Cell Biology
Molecular Biology

Date 2019 Jun 13

PMID 31185583

Citations 5

Authors

Jia-Hao Wang

Yan Li

Shou-Long Deng

Yi-Xun Liu

Zheng-Xing Lian

Kun Yu

Affiliations

Soon will be listed here.

Abstract

Mitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis. In the past few years, substantial research progress has been made by showing that cyclins/cyclin-dependent kinase (CDK) have roles in the regulation of meiosis. In addition, more functional signaling molecules have been discovered in mitosis. Growing evidence has also indicated that miRNAs influence cell cycling. In this review, we focus on specific genes, cyclins/Cdk, signaling pathways/molecules, and miRNAs to discuss the latest achievements in understanding their roles in mitosis during gametogenesis. Further elucidation of mitosis during gametogenesis may facilitate delineating all processes of mammalian reproduction and the development of disease treatments.

Citing Articles

Pregametogenesis: The Earliest Stages of Gonad and Germline Differentiation in Anuran Amphibians.

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PMID: 39765684 PMC: 11673927. DOI: 10.3390/biology13121017.

The Role of Retinoic Acid in Spermatogenesis and Its Application in Male Reproduction.

Zhao Y, Deng S, Li C, Cao J, Wu A, Chen M Cells. 2024; 13(13.

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Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review.

Fayezi S, Fayyazpour P, Norouzi Z, Mehdizadeh A Cell J. 2022; 24(8):434-441.

PMID: 36093802 PMC: 9468722. DOI: 10.22074/cellj.2022.8087.

Contextualizing Autophagy during Gametogenesis and Preimplantation Embryonic Development.

Moura M, Latorraca L, Paula-Lopes F Int J Mol Sci. 2021; 22(12).

PMID: 34204653 PMC: 8231133. DOI: 10.3390/ijms22126313.

Regulation of chromatin structure and function: insights into the histone chaperone FACT.

Wang P, Yang W, Zhao S, Nashun B Cell Cycle. 2021; 20(5-6):465-479.

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