Quantitative in Vivo Assessment of Bone Allograft Viability Using F-fluoride PET/CT After Glenoid Augmentation in Reverse Shoulder Arthroplasty: a Pilot Study

Overview

Journal Eur J Orthop Surg Traumatol

Specialty Orthopedics

Date 2019 Jun 8

PMID 31172286

Citations 3

Authors

Josef Hochreiter

Georg Mattiassich

Wolfgang Hitzl

Georg Weber

Mohsen Beheshti

Reinhold Ortmaier

Affiliations

Soon will be listed here.

Abstract

Background: Success after glenoid bone augmentation in total shoulder arthroplasty depends on osseous integration and non-resorption. Standard imaging techniques, such as computed tomography (CT) and X-rays, cannot quantify bone viability. Therefore, we introduce a new technique to assess graft viability using F-sodium fluoride (F-NaF) PET-CT for femoral allografts in reverse total shoulder arthroplasty (RSA).

Materials And Methods: Patient charts were reviewed following glenoid augmentation using femoral allografts in reverse total shoulder arthroplasty. A total of seven patients were included in this study. F-NaF PET-CT was used to assess graft viability and graft fusion. Semiquantitative assessment of F-NaF uptake was performed by means of a standardized uptake value (SUV). Radiographs were used to assess fusion. The mean age of the patients at the time of follow-up was 83.4 years (range 79-92), and the mean follow-up was 44.4 months.

Results: Viability and fusion were confirmed in all allografts using semiquantitative analysis of F-NaF PET-CT by means of standardized uptake value (SUVmax). Metabolic activity of medullary region of a vertebral spine was defined as a reference background. The mean value of maximum tracer activity in the allograft was not statistically different from native bone in the reference vertebrae (p = 0.14).

Conclusions: F-NaF PET-CT is a practicable tool to quantitatively assess viability in large bone allografts after glenoid augmentation in RSA. The study shows viability and fusion in all allografts.

Level Of Evidence: Level IV, treatment study.

Citing Articles

Validation of quantitative [F]NaF PET uptake parameters in bone diseases: a systematic review.

de Ruiter R, Zwama J, Raijmakers P, Yaqub M, Burchell G, Boellaard R Ann Nucl Med. 2024; 39(2):98-149.

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A narrative review of treatment strategies for major glenoid defects during primary reverse shoulder arthroplasty, with a focus on the use of structural bone graft.

Rachuene P, Dey R, Sivarasu S, du Plessis J, Roche S, Vrettos B EFORT Open Rev. 2023; 8(10):759-770.

PMID: 37787496 PMC: 10562945. DOI: 10.1530/EOR-22-0062.

Survivorship of Allologous Structural Bone Graft at a Minimum of 2 Years When Used to Address Significant Glenoid Bone Loss in Revision Shoulder Arthroplasty: A Computed Tomographic and Clinical Review.

Viswanath A, Newell A, Cunningham L, Walton M, Monga P, Bale S J Shoulder Elb Arthroplast. 2023; 7:24715492231172371.

PMID: 37197294 PMC: 10184218. DOI: 10.1177/24715492231172371.

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