Identification of Bovine Papillomavirus Type 1 and 2 from Bovine Anogenital Fibropapillomas

Overview

Journal J Vet Med Sci

Specialty Veterinary Medicine

Date 2019 Jun 4

PMID 31155549

Citations 4

Authors

Nanako Yamashita-Kawanishi

Masano Tsuzuki

Zhu Wei

Mun Keong Kok

Dai Ishiyama

James K Chambers

Kazuyuki Uchida

Jianbao Dong

Hidekatsu Shimakura

Takeshi Haga

Affiliations

Soon will be listed here.

Abstract

Papillomavirus (PV) is a well-known pathogen associated with epithelial and mucosal neoplastic diseases. In contrast to human PVs, characterization of animal PVs from the aspect of anogenital neoplasm is still on a learning curve. In the present study, two vulval and one anal warts, histologically diagnosed as fibropapillomas, excised from dairy cattle were analyzed. PCR and sequencing revealed that bovine papillomavirus type 1 (BPV-1) and BPV-2 were detected from anal and vulval fibropapillomas, respectively. Immunohistochemistry detected PV antigen in a few differentiated keratinocytes of one vulval case. Reverse-transcriptase PCR detected the early region, but not the late region of BPV mRNA in all three cases. The present study will provide new insight into the relationship between BPV and anogenital papilloma in cattle.

Citing Articles

An investigation of bovine papillomaviruses from ocular squamous cell carcinomas in cattle.

Karakurt E, Coskun N, Aydin U, Beytut E, Dag S, Ataseven V Iran J Vet Res. 2023; 24(1):51-57.

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Molecular detection of Papillomavirus and immunohistochemical investigation of p53 gene expressions in bovine papillomas and fibropapillomas.

Emin K, Nuvit C, Serpil D, Enver B, Ataseven V, Volkan Y Arch Microbiol. 2022; 204(5):278.

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Full-genome characterization of a novel Felis catus papillomavirus 4 subtype identified in a cutaneous squamous cell carcinoma of a domestic cat.

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PMID: 34037953 DOI: 10.1007/s11262-021-01843-y.

Anogenital-Associated Papillomaviruses in Animals: Focusing on Papillomaviruses.

Yamashita-Kawanishi N, Haga T Pathogens. 2020; 9(12).

PMID: 33260814 PMC: 7760238. DOI: 10.3390/pathogens9120993.

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