» Articles » PMID: 31143726

Diagnosis of Envenomation by Russell's and Echis Carinatus Viper: A Clinical Study at Rural Maharashtra State of India

Overview
Specialty Public Health
Date 2019 May 31
PMID 31143726
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Envenoming by vipers and are common accidents faced by farmers and labors. Both viper venom toxins alter coagulation mechanism in the victim. The dose of snake antivenin to neutralize the venom is empirical and varies. Though the clinical manifestations in both vipers bite envenoming are nearly similar but dose of antivenin required is more in . We studied in detail about the correlation of clinical manifestations and confirmed species of snake.

Methods: Cases of vipers snake bites admitted for last two successive years were studied. Analysis by local manifestations, systemic involvement, 20 minute whole blood clotting test (20WBCT), identification of snake responsible for clinical effects are confirmed by the snake species brought by victims or bystanders, in case of where victim saw the snake bur failed to kill. The victims identified from pictures of big four poisonous snakes (, , Cobra, and krait). Further confirmation from the species responsible is done by showing the hospital preserved specimen to identify the culprits.

Findings: About 77 cases of viper bite studied of these 57 has clinical syndrome suggestive of (RV) bite, one has dry bite, 23 victims brought the killed specimen confirmed RV, of these 18 identified the specimen picture and 5 wrongly locate the species in pictures, 20 victims correctly identified the hospital preserved specimen while 3 failed to recognize. There were 28 patients who saw the snake while bitten but failed to kill, of these 20 patients identify correctly the species on picture while 8 failed to identify. Only 22 correctly identified the culprit by looking at the hospital preserved specimen and 6 were confused. One dry bite victim correctly identified the bitten snake species in picture and hospital preserved specimen.

Interpretation: In viper bite poisoning clinical pictures and hospital specimen help to confirm the species are highly supportive for clinical diagnosis.

Citing Articles

Medical management of a child treated for two unique envenomation episodes via captive snakes in a 60-day period: A case report.

Gao M, Zhang X, Jian T, Sun C, Yu G, Gao Y Heliyon. 2025; 10(22):e40245.

PMID: 39748992 PMC: 11693922. DOI: 10.1016/j.heliyon.2024.e40245.


Prevention & management of snakebite envenomation: A qualitative study on perspectives & practices in Maharashtra & Odisha.

Munshi H, Gavhande M, Bhad G, Mohanty B, Dash J, Madavi K Indian J Med Res. 2024; 159(3 & 4):356-368.

PMID: 39361800 PMC: 11414789. DOI: 10.25259/IJMR_1566_23.


Challenges and Opportunities in Clinical Diagnostic Routine of Envenomation Using Blood Plasma Proteomics.

Cavalcante J, de Almeida D, Moraes M, Santos S, Moriel Pincinato P, Riciopo P Toxins (Basel). 2023; 15(3).

PMID: 36977071 PMC: 10056359. DOI: 10.3390/toxins15030180.


Current Knowledge on Snake Dry Bites.

Pucca M, Knudsen C, Oliveira I, Rimbault C, Cerni F, Wen F Toxins (Basel). 2020; 12(11).

PMID: 33105644 PMC: 7690386. DOI: 10.3390/toxins12110668.


Collocation of avian and mammal antibodies to develop a rapid and sensitive diagnostic tool for Russell's Vipers Snakebite.

Lin J, Lo C, Chuang S, Chiang C, Wang S, Lin T PLoS Negl Trop Dis. 2020; 14(9):e0008701.

PMID: 32956365 PMC: 7529284. DOI: 10.1371/journal.pntd.0008701.


References
1.
. WHO/SEARO Guidelines for the clinical management of snake bites in the Southeast Asian region. Southeast Asian J Trop Med Public Health. 2000; 30 Suppl 1:1-85. View

2.
Bawaskar H, Bawaskar P . Call for global snake-bite control and procurement funding. Lancet. 2001; 357(9262):1132-3. DOI: 10.1016/s0140-6736(00)04286-0. View

3.
McNamee D . Tackling venomous snake bites worldwide. Lancet. 2001; 357(9269):1680. DOI: 10.1016/S0140-6736(00)04868-6. View

4.
Bawaskar H, Bawaskar P . Profile of snakebite envenoming in western Maharashtra, India. Trans R Soc Trop Med Hyg. 2002; 96(1):79-84. DOI: 10.1016/s0035-9203(02)90250-6. View

5.
Bawaskar H, Bawaskar P . Aphasia in a farmer after viper bite. Lancet. 2002; 360(9346):1703. DOI: 10.1016/s0140-6736(02)11640-0. View