Circulating Tumor Cells in the Clinical Cancer Diagnosis
Overview
Affiliations
Circulating tumor cells (CTCs) are cells that have shed into the vasculature or lymphatics from a primary tumor and are carried around the body in the blood circulation. CTCs undergo a series of migration, adhesion and aggregation to form metastases, leading to post-operative recurrence and metastasis in patients with malignant tumors. The detection and analysis of CTCs, as a new non-invasive diagnostic tool, plays an important role in tumor diagnosis, therapeutic efficacy, monitoring recurrence, prognosis assessment and tumor precision medical treatment.
Minkler S, Lucien F, Kimber M, Sahoo D, Bourgois-Mochel A, Musser M Cancers (Basel). 2021; 13(3).
PMID: 33498666 PMC: 7865365. DOI: 10.3390/cancers13030422.