SnRK1 Kinase and the NAC Transcription Factor SOG1 Are Components of a Novel Signaling Pathway Mediating the Low Energy Response Triggered by ATP Depletion

Overview

Journal Front Plant Sci

Date 2019 May 29

PMID 31134102

Citations 12

Authors

Hidefumi Hamasaki

Yukio Kurihara

Takashi Kuromori

Hiroaki Kusano

Noriko Nagata

Yoshiharu Y Yamamoto

Hiroaki Shimada

Minami Matsui

Affiliations

Soon will be listed here.

Abstract

Plant growth is strictly controlled by cell division, elongation, and differentiation for which adequate supplies of intracellular ATP are required. However, it is unclear how changes in the amount of intracellular ATP affect cell division and growth. To reveal the specific pathway dependent on ATP concentration, we performed analyses on the mitochondria mutation . The mutant is tiny, a result of a low amount of ATP caused by the disruption of Tim21, a subunit of the TIM23 protein complex localized in the inner membrane of the mitochondria. Loss of function of () also restored the dwarf phenotype of wild type treated with antimycin A, a blocker of ATP synthesis in mitochondria. The phenotype is partially restored by the introduction of , and /, subunits of Snf1-related kinase 1 (SnRK1). Additionally, SOG1 interacted with SnRK1, and was modified by phosphorylation only after treatment with antimycin A. Transcripts of several negative regulators of the endocycle were up-regulated in the mutant, and this high expression was not observed in and . We suggest that there is a novel regulatory mechanism for the control of plant cell cycle involving SnRK1 and SOG1, which is induced by low amounts of intracellular ATP, and controls plant development.

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