[Infantile Haemangioma: An update]

Overview

Journal Hautarzt

Specialty Dermatology

Date 2019 May 19

PMID 31101924

Citations 2

Authors

Antonia Reimer

Hagen Ott

Affiliations

Soon will be listed here.

Abstract

Infantile haemangioma (IH) are the most frequent skin tumors in childhood. The diagnosis is usually established from the clinical picture and typical course of growth. Sectional imaging procedures are indicated in segmental, especially facial haemangiomas. The vast majority of IH are uncomplicated and do not require any treatment. In complicated IH, treatment should be initiated as soon as possible in order to avoid permanent damage. Propranolol is the treatment of choice for complicated IH.

Citing Articles

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Low-dose sclerotherapy with lauromacrogol in the treatment of infantile hemangiomas: A retrospective analysis of 368 cases.

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References

North P, Waner M, Mizeracki A, Mrak R, Nicholas R, Kincannon J . A unique microvascular phenotype shared by juvenile hemangiomas and human placenta. Arch Dermatol. 2001; 137(5):559-70. View

Metry D, Dowd C, Barkovich A, Frieden I . The many faces of PHACE syndrome. J Pediatr. 2001; 139(1):117-23. DOI: 10.1067/mpd.2001.114880. View

Chiller K, Passaro D, Frieden I . Hemangiomas of infancy: clinical characteristics, morphologic subtypes, and their relationship to race, ethnicity, and sex. Arch Dermatol. 2002; 138(12):1567-76. DOI: 10.1001/archderm.138.12.1567. View

Hughes J, Hill V, Patel K, Syed S, Harper J, De Bruyn R . Cutaneous haemangioma: prevalence and sonographic characteristics of associated hepatic haemangioma. Clin Radiol. 2004; 59(3):273-80. DOI: 10.1016/S0009-9260(03)00267-8. View

Metry D, Haggstrom A, Drolet B, Baselga E, Chamlin S, Garzon M . A prospective study of PHACE syndrome in infantile hemangiomas: demographic features, clinical findings, and complications. Am J Med Genet A. 2006; 140(9):975-86. DOI: 10.1002/ajmg.a.31189. View

Girard C, Bigorre M, Guillot B, Bessis D . PELVIS Syndrome. Arch Dermatol. 2006; 142(7):884-8. DOI: 10.1001/archderm.142.7.884. View

Haggstrom A, Drolet B, Baselga E, Chamlin S, Garzon M, Horii K . Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics. J Pediatr. 2007; 150(3):291-4. DOI: 10.1016/j.jpeds.2006.12.003. View

Chamlin S, Haggstrom A, Drolet B, Baselga E, Frieden I, Garzon M . Multicenter prospective study of ulcerated hemangiomas. J Pediatr. 2007; 151(6):684-9, 689.e1. DOI: 10.1016/j.jpeds.2007.04.055. View

Heyer G, Dowling M, Licht D, Tay S, Morel K, Garzon M . The cerebral vasculopathy of PHACES syndrome. Stroke. 2008; 39(2):308-16. DOI: 10.1161/STROKEAHA.107.485185. View

10.

Oza V, Wang E, Berenstein A, Waner M, Lefton D, Wells J . PHACES association: a neuroradiologic review of 17 patients. AJNR Am J Neuroradiol. 2008; 29(4):807-13. PMC: 7978195. DOI: 10.3174/ajnr.A0937. View

11.

Leaute-Labreze C, Dumas de la Roque E, Hubiche T, Boralevi F, Thambo J, Taieb A . Propranolol for severe hemangiomas of infancy. N Engl J Med. 2008; 358(24):2649-51. DOI: 10.1056/NEJMc0708819. View

12.

Chang L, Haggstrom A, Drolet B, Baselga E, Chamlin S, Garzon M . Growth characteristics of infantile hemangiomas: implications for management. Pediatrics. 2008; 122(2):360-7. DOI: 10.1542/peds.2007-2767. View

13.

Metry D, Heyer G, Hess C, Garzon M, Haggstrom A, Frommelt P . Consensus Statement on Diagnostic Criteria for PHACE Syndrome. Pediatrics. 2009; 124(5):1447-56. DOI: 10.1542/peds.2009-0082. View

14.

Storch C, Hoeger P . Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action. Br J Dermatol. 2010; 163(2):269-74. DOI: 10.1111/j.1365-2133.2010.09848.x. View

15.

Iacobas I, Burrows P, Frieden I, Liang M, Mulliken J, Mancini A . LUMBAR: association between cutaneous infantile hemangiomas of the lower body and regional congenital anomalies. J Pediatr. 2010; 157(5):795-801.e1-7. DOI: 10.1016/j.jpeds.2010.05.027. View

16.

Osio A, Fraitag S, Hadj-Rabia S, Bodemer C, de Prost Y, Hamel-Teillac D . Clinical spectrum of tufted angiomas in childhood: a report of 13 cases and a review of the literature. Arch Dermatol. 2010; 146(7):758-63. DOI: 10.1001/archdermatol.2010.135. View

17.

Hess C, Fullerton H, Metry D, Drolet B, Siegel D, Auguste K . Cervical and intracranial arterial anomalies in 70 patients with PHACE syndrome. AJNR Am J Neuroradiol. 2010; 31(10):1980-6. PMC: 5967888. DOI: 10.3174/ajnr.A2206. View

18.

Suh K, Frieden I . Infantile hemangiomas with minimal or arrested growth: a retrospective case series. Arch Dermatol. 2010; 146(9):971-6. DOI: 10.1001/archdermatol.2010.197. View

19.

Bauland C, Luning T, Smit J, Zeebregts C, Spauwen P . Untreated hemangiomas: growth pattern and residual lesions. Plast Reconstr Surg. 2011; 127(4):1643-1648. DOI: 10.1097/PRS.0b013e318208d2ac. View

20.

Horii K, Drolet B, Frieden I, Baselga E, Chamlin S, Haggstrom A . Prospective study of the frequency of hepatic hemangiomas in infants with multiple cutaneous infantile hemangiomas. Pediatr Dermatol. 2011; 28(3):245-53. DOI: 10.1111/j.1525-1470.2011.01420.x. View