Circadian and Circannual Regulation in the Horse: Internal Timing in an Elite Athlete

Biological rhythms evolved to provide temporal coordination across all tissues and organs and allow synchronization of physiology with predictable environmental cycles. Most important of these are circadian and circannual rhythms, primarily regulated via photoperiod signals from the retina. Understanding the nature of physiological rhythms in horses is crucially important for equine management. Predominantly, they have been removed from exposure to their natural environmental stimuli; the seasonally changing photoperiod, continuous foraging and feeding activity, social herd interactions, and the continuous low-intensity exercise of a grassland dweller. These have been replaced in many cases with confined indoor housing, regimental feeding and exercise times, social isolation, and exposure to lighting that is often erratic and does not come close to mimicking the spectral composition of sunlight. Man has further altered seasonal timing cues through the use of artificial lighting programs that impact reproductive behavior, breeding efficiency, and the development of youngstock. Understanding how these new environmental cues (some stronger and some weaker) impact the internal physiology of the horse in the context of the natural endogenous rhythms that evolved over millennia is key to helping to improve equine health, welfare, and performance, now and into the future. This review provides an overview of the field, highlights the recent discoveries related to biological timing in horses, and discusses the implications that these findings may have for the production and management of the elite equine athlete.