» Articles » PMID: 31079441

Detecting Peripheral Arterial Disease in Primary Care: A Population Based Study

Overview
Specialty Public Health
Date 2019 May 14
PMID 31079441
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Peripheral arterial disease (PAD) can progress silently without any clinical symptoms. Ankle-brachial index (ABI) is the recommended method used in primary care. We aimed to determine the prevalence of PAD and its related risk factors in primary care.

Methods: In this cross-sectional study, 250 participants aged ≥45 years were recruited randomly from the registered patients of family health center in a district of Izmir, Turkey. Patients' demographic data, PAD symptoms, and PAD risk factors were obtained. The PAD group consisted of patients with ABI levels <0.9; the non-compressible artery (NCA) group consisted of patients with ABI levels >1.3.

Results: The prevalence of PAD was 17.6% (22.5% in women and 11.1% in men), while that of NCA was 15.2% (12.7% in women and 25.0% in men). About 27.3% and 54.5% of patients with PAD did not have claudication and problems with walking distance, respectively. Of the NCA patients, 15.8% had problems with walking distance and 39.5% had claudication. Regression analysis revealed two predictors of PAD (age ≥65 years: odds ratio [OR], 3.51; 95% confidence interval [CI], 1.65-7.47; claudication: OR, 3.41; 95% CI, 1.58-7.39) and three predictors of NCA (age <65 years: OR, 2.55; 95% CI, 1.01-6.45; male sex: OR, 2.40; 95% CI, 1.10-5.25; triglyceride [TG] >200 mg/dL: OR, 4.11; 95% CI, 1.58-10.67).

Conclusion: PAD had a prevalence of 17.6% and was associated with age ≥65 years and claudication. NCA had a prevalence of 15.2% and was associated with age <65 years, TG >200 mg/dL, and male sex.

Citing Articles

The Frequency of Primary Healthcare Contacts Preceding the Diagnosis of Lower-Extremity Arterial Disease: Do Women Consult General Practice Differently?.

Porras C, Teraa M, Bots M, de Boer A, Peters S, van Doorn S J Clin Med. 2022; 11(13).

PMID: 35806951 PMC: 9267865. DOI: 10.3390/jcm11133666.

References
1.
Meijer W, Grobbee D, Hunink M, Hofman A, Hoes A . Determinants of peripheral arterial disease in the elderly: the Rotterdam study. Arch Intern Med. 2000; 160(19):2934-8. DOI: 10.1001/archinte.160.19.2934. View

2.
Hooi J, Kester A, Stoffers H, Rinkens P, Knottnerus J, Van Ree J . Asymptomatic peripheral arterial occlusive disease predicted cardiovascular morbidity and mortality in a 7-year follow-up study. J Clin Epidemiol. 2004; 57(3):294-300. DOI: 10.1016/j.jclinepi.2003.09.003. View

3.
Selvin E, Erlinger T . Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999-2000. Circulation. 2004; 110(6):738-43. DOI: 10.1161/01.CIR.0000137913.26087.F0. View

4.
Zanati S, Mouraria G, Matsubara L, Giannini M, Matsubara B . Profile of cardiovascular risk factors and mortality in patients with symptomatic peripheral arterial disease. Clinics (Sao Paulo). 2009; 64(4):323-6. PMC: 2694468. DOI: 10.1590/s1807-59322009000400010. View

5.
Xu D, Li J, Zou L, Xu Y, Hu D, Pagoto S . Sensitivity and specificity of the ankle--brachial index to diagnose peripheral artery disease: a structured review. Vasc Med. 2010; 15(5):361-9. DOI: 10.1177/1358863X10378376. View