Wearable Devices for Single-Cell Sensing And Transfection

Overview

Journal Trends Biotechnol

Specialty Biochemistry

Date 2019 May 11

PMID 31072609

Citations 8

Authors

Lingqian Chang

Yu-Chieh Wang

Faheem Ershad

Ruiguo Yang

Cunjiang Yu

Yubo Fan

Affiliations

Soon will be listed here.

Abstract

Wearable healthcare devices are mainly used for biosensing and transdermal delivery. Recent advances in wearable biosensors allow for long-term and real-time monitoring of physiological conditions at a cellular resolution. Transdermal drug delivery systems have been further scaled down, enabling wide selections of cargo, from natural molecules (e.g., insulin and glucose) to bioengineered molecules (e.g., nanoparticles). Some emerging nanopatches show promise for precise single-cell gene transfection in vivo and have advantages over conventional tools in terms of delivery efficiency, safety, and controllability of delivered dose. In this review, we discuss recent technical advances in wearable micro/nano devices with unique capabilities or potential for single-cell biosensing and transfection in the skin or other organs, and suggest future directions for these fields.

Citing Articles

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Wearable Bioelectronics for Chronic Wound Management.

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