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Status Epilepticus and Bilateral Middle Cerebral Artery Infarction: A Rare Presentation After Viper Bite

Overview
Journal Ann Afr Med
Specialty General Medicine
Date 2019 May 10
PMID 31070155
Citations 2
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Abstract

Owing to the antihemostatic property of viper venom, hemorrhagic complications including intracerebral hemorrhage are the most commonly encountered after viper bite. Ischemic strokes have been rarely reported after viper envenomation, and its occurrence has been attributed to multiple mechanisms. Postsnakebite seizures are known to occur after neurotoxic bite. Here, we report the case of a viper bite victim who developed status epilepticus within 3 h after viper bite. He had only mild signs of local envenomation, and prolonged whole blood clotting time was the only manifestation of systemic envenomation. Subsequently, he was found to have developed right hemiparesis and global aphasia. Brain imaging revealed large infarcts in bilateral middle cerebral artery (MCA) territories. We report this as a unique case of viper bite which presented to the emergency room with status epilepticus. Moreover, bilateral MCA infarct, as was found in this case, is genuinely rare in scientific literature. Finally, the absence of overt features of envenomation makes this case stand out from other similar reported occurrences.

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References
1.
Bagetta G, Iannone M, Palma E, Nistico G, Dolly J . N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors mediate seizures and CA1 hippocampal damage induced by dendrotoxin-K in rats. Neuroscience. 1996; 71(3):613-24. DOI: 10.1016/0306-4522(95)00502-1. View

2.
Gouda S, Pandit V, Seshadri S, Valsalan R, Vikas M . Posterior circulation ischemic stroke following Russell's viper envenomation. Ann Indian Acad Neurol. 2012; 14(4):301-3. PMC: 3271473. DOI: 10.4103/0972-2327.91957. View

3.
Paul G, Paul B, Puri S . Snake bite and stroke: Our experience of two cases. Indian J Crit Care Med. 2014; 18(4):257-8. PMC: 4033865. DOI: 10.4103/0972-5229.130585. View

4.
Mosquera A, Idrovo L, Tafur A, Del Brutto O . Stroke following Bothrops spp. snakebite. Neurology. 2003; 60(10):1577-80. DOI: 10.1212/01.wnl.0000061614.52580.a1. View

5.
Bagetta G, Nistico G, Dolly J . Production of seizures and brain damage in rats by alpha-dendrotoxin, a selective K+ channel blocker. Neurosci Lett. 1992; 139(1):34-40. DOI: 10.1016/0304-3940(92)90851-w. View