BRCAness in Prostate Cancer

Overview

Journal Oncotarget

Specialty Oncology

Date 2019 May 10

PMID 31069005

Citations 6

Authors

Natalia Bednarz-Knoll

Elke Eltze

Axel Semjonow

Burkhard Brandt

Affiliations

Soon will be listed here.

Citing Articles

BRCA1 & BRCA2 methylation as a prognostic and predictive biomarker in cancer: Implementation in liquid biopsy in the era of precision medicine.

Panagopoulou M, Panou T, Gkountakos A, Tarapatzi G, Karaglani M, Tsamardinos I Clin Epigenetics. 2024; 16(1):178.

PMID: 39643918 PMC: 11622545. DOI: 10.1186/s13148-024-01787-8.

Emerin mislocalization during chromatin bridge resolution can drive prostate cancer cell invasiveness in a collagen-rich microenvironment.

Popeda M, Kowalski K, Wenta T, Beznoussenko G, Rychlowski M, Mironov A Exp Mol Med. 2024; 56(9):2016-2032.

PMID: 39218980 PMC: 11446916. DOI: 10.1038/s12276-024-01308-w.

DNA repair deficiency as circulating biomarker in prostate cancer.

Catalano M, Generali D, Gatti M, Riboli B, Paganini L, Nesi G Front Oncol. 2023; 13:1115241.

PMID: 36793600 PMC: 9922904. DOI: 10.3389/fonc.2023.1115241.

BRCA Mutations in Prostate Cancer: Assessment, Implications and Treatment Considerations.

Shah S, Rachmat R, Enyioma S, Ghose A, Revythis A, Boussios S Int J Mol Sci. 2021; 22(23).

PMID: 34884434 PMC: 8657599. DOI: 10.3390/ijms222312628.

Circulating Tumor DNA Testing for Homology Recombination Repair Genes in Prostate Cancer: From the Lab to the Clinic.

Cimadamore A, Cheng L, Massari F, Santoni M, Pepi L, Franzese C Int J Mol Sci. 2021; 22(11).

PMID: 34073818 PMC: 8197269. DOI: 10.3390/ijms22115522.

References

Schmidt H, DeAngelis G, Eltze E, Gockel I, Semjonow A, Brandt B . Asynchronous growth of prostate cancer is reflected by circulating tumor cells delivered from distinct, even small foci, harboring loss of heterozygosity of the PTEN gene. Cancer Res. 2006; 66(18):8959-65. DOI: 10.1158/0008-5472.CAN-06-1722. View

Ginestier C, Liu S, Wicha M . Getting to the root of BRCA1-deficient breast cancer. Cell Stem Cell. 2009; 5(3):229-30. DOI: 10.1016/j.stem.2009.08.007. View

Bednarz N, Eltze E, Semjonow A, Rink M, Andreas A, Mulder L . BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood. Clin Cancer Res. 2010; 16(13):3340-8. PMC: 3042432. DOI: 10.1158/1078-0432.CCR-10-0150. View

Burga L, Hu H, Juvekar A, Tung N, Troyan S, Hofstatter E . Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice. Breast Cancer Res. 2011; 13(2):R30. PMC: 3219192. DOI: 10.1186/bcr2850. View

Ibeawuchi C, Schmidt H, Voss R, Titze U, Abbas M, Neumann J . Exploring prostate cancer genome reveals simultaneous losses of PTEN, FAS and PAPSS2 in patients with PSA recurrence after radical prostatectomy. Int J Mol Sci. 2015; 16(2):3856-69. PMC: 4346930. DOI: 10.3390/ijms16023856. View

Lord C, Ashworth A . BRCAness revisited. Nat Rev Cancer. 2016; 16(2):110-20. DOI: 10.1038/nrc.2015.21. View

Lecarpentier J, Silvestri V, Kuchenbaecker K, Barrowdale D, Dennis J, McGuffog L . Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. J Clin Oncol. 2017; 35(20):2240-2250. PMC: 5501359. DOI: 10.1200/JCO.2016.69.4935. View

Heijnsdijk E, Bangma C, Borras J, M de Carvalho T, Castells X, Eklund M . Summary statement on screening for prostate cancer in Europe. Int J Cancer. 2017; 142(4):741-746. DOI: 10.1002/ijc.31102. View

Rescigno P, Chandler R, de Bono J . Relevance of poly (ADP-ribose) polymerase inhibitors in prostate cancer. Curr Opin Support Palliat Care. 2018; 12(3):339-343. DOI: 10.1097/SPC.0000000000000358. View

10.

Reiter J, Makohon-Moore A, Gerold J, Heyde A, Attiyeh M, Kohutek Z . Minimal functional driver gene heterogeneity among untreated metastases. Science. 2018; 361(6406):1033-1037. PMC: 6329287. DOI: 10.1126/science.aat7171. View

11.

Omari A, Nastaly P, Stoupiec S, Balabas A, Dabrowska M, Bielinska B . Somatic aberrations of BRCA1 gene are associated with ALDH1, EGFR, and tumor progression in prostate cancer. Int J Cancer. 2018; 144(3):607-614. DOI: 10.1002/ijc.31905. View