Diethylzinc-Mediated Metalloamination-Alkylation of , -Dimethylhydrazinoalkenes. Catalysis of C-Zn Alkylation Using Simple Cu(I) Salts

Overview

Journal Synlett

Specialty Chemistry

Date 2019 May 10

PMID 31068740

Citations 2

Authors

Ky Mickelsen

Sean Zabawa

Tom Livinghouse

Affiliations

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Abstract

Metalloamination-alkylation of representative ,-dimethyl-hydrazinoalkenes has been shown to be effectively catalyzed by CuBr-SMe, CuCN, and Cul. The current method obviates the use of stoichiometric CuCN(LiCl) as a promoter for the electrophilic functionalization event.

Citing Articles

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Copper(I)-Catalyzed Cross-Coupling of 1-Bromoalkynes with N-Heterocyclic Organozinc Reagents.

Frabitore C, Lepeule J, Livinghouse T Molecules. 2022; 27(14).

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