Depressed Non-specific Lymphocyte Reactivity in Psoriasis

Overview

Journal Arch Dermatol Res

Specialty Dermatology

Date 1978 Nov 10

PMID 310658

Citations 1

Authors

L Lindholm

B L Magnusson

H Mobacken

Affiliations

Soon will be listed here.

Abstract

T-lymphocyte number and functions were studied in 24 patients with psoriasis guttata as compared to healthy controls. A decrease was found of the in vitro ability to synthetize DNA in response to stimulation with phytohemagglutinin (PHA), concanavalin A, poke weed mitogen and PPD, which was statistically significant for PHA. The percentage and absolute numbers of both T and B peripheral blood lymphocytes were not altered.

Citing Articles

Immunological features of psoriasis. Effects of Ro-109359, concanavalin A, pokeweed mitogen, and methotrexate on cultivated lymphocytes.

Bialasiewicz A, Lubach D, MARGHESCU S Arch Dermatol Res. 1981; 271(1):29-40.

PMID: 7294881 DOI: 10.1007/BF00417385.

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