Key Paediatric Messages from the 2018 European Respiratory Society International Congress

Overview

Journal ERJ Open Res

Specialty Pulmonary Medicine

Date 2019 May 3

PMID 31044141

Authors

Raffaella Nenna

Katie A Hunt

Theodore Dassios

Jennifer J P Collins

Robbert J Rottier

Norrice M Liu

Bart Rottier

Myrofora Goutaki

Bulent Karadag

Andrew Prayle

Ricardo M Fernandes

Giuseppe Fabio Parisi

Jurg Barben

Bruna Rubbo

Deborah Snijders

Heidi Makrinioti

Graham Hall

Marielle W Pijnenburg

Jonathan Grigg

Affiliations

Soon will be listed here.

Abstract

In this article, the Group Chairs and early career members of the European Respiratory Society (ERS) Paediatric Assembly highlight some of the most interesting findings in the field of paediatrics which were presented at the 2018 international ERS Congress.

References

Kobbernagel H, Buchvald F, Haarman E, Casaulta C, Collins S, Hogg C . Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6 months in primary ciliary dyskinesia. BMC Pulm Med. 2016; 16(1):104. PMC: 4957315. DOI: 10.1186/s12890-016-0261-x. View

Jaddoe V, Van Duijn C, Franco O, van der Heijden A, van Iizendoorn M, de Jongste J . The Generation R Study: design and cohort update 2012. Eur J Epidemiol. 2012; 27(9):739-56. DOI: 10.1007/s10654-012-9735-1. View

Shapiro A, Davis S, Polineni D, Manion M, Rosenfeld M, Dell S . Diagnosis of Primary Ciliary Dyskinesia. An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2018; 197(12):e24-e39. PMC: 6006411. DOI: 10.1164/rccm.201805-0819ST. View

Elborn J . Cystic fibrosis. Lancet. 2016; 388(10059):2519-2531. DOI: 10.1016/S0140-6736(16)00576-6. View

Claudia F, Thiering E, von Berg A, Berdel D, Hoffmann B, Koletzko S . Peak weight velocity in infancy is negatively associated with lung function in adolescence. Pediatr Pulmonol. 2015; 51(2):147-56. DOI: 10.1002/ppul.23216. View

Shah A, Shoemark A, MacNeill S, Bhaludin B, Rogers A, Bilton D . A longitudinal study characterising a large adult primary ciliary dyskinesia population. Eur Respir J. 2016; 48(2):441-50. DOI: 10.1183/13993003.00209-2016. View

Fens N, Zwinderman A, Van Der Schee M, de Nijs S, Dijkers E, Roldaan A . Exhaled breath profiling enables discrimination of chronic obstructive pulmonary disease and asthma. Am J Respir Crit Care Med. 2009; 180(11):1076-82. DOI: 10.1164/rccm.200906-0939OC. View

Bannier M, van de Kant K, Jobsis Q, Dompeling E . Feasibility and diagnostic accuracy of an electronic nose in children with asthma and cystic fibrosis. J Breath Res. 2018; 13(3):036009. DOI: 10.1088/1752-7163/aae158. View

Paff T, Daniels J, Weersink E, Lutter R, Vonk Noordegraaf A, Haarman E . A randomised controlled trial on the effect of inhaled hypertonic saline on quality of life in primary ciliary dyskinesia. Eur Respir J. 2017; 49(2). DOI: 10.1183/13993003.01770-2016. View

10.

Knowles M, Ostrowski L, Leigh M, Sears P, Davis S, Wolf W . Mutations in RSPH1 cause primary ciliary dyskinesia with a unique clinical and ciliary phenotype. Am J Respir Crit Care Med. 2014; 189(6):707-17. PMC: 3983840. DOI: 10.1164/rccm.201311-2047OC. View

11.

Brand P, Baraldi E, Bisgaard H, Boner A, Castro-Rodriguez J, Custovic A . Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J. 2008; 32(4):1096-110. DOI: 10.1183/09031936.00002108. View

12.

Townshend J, Hails S, McKean M . Diagnosis of asthma in children. BMJ. 2007; 335(7612):198-202. PMC: 1934462. DOI: 10.1136/bmj.39234.651412.AE. View

13.

Leigh M, Ferkol T, Davis S, Lee H, Rosenfeld M, Dell S . Clinical Features and Associated Likelihood of Primary Ciliary Dyskinesia in Children and Adolescents. Ann Am Thorac Soc. 2016; 13(8):1305-13. PMC: 5021075. DOI: 10.1513/AnnalsATS.201511-748OC. View

14.

Connelly R, Platt L . Cohort profile: UK Millennium Cohort Study (MCS). Int J Epidemiol. 2014; 43(6):1719-25. DOI: 10.1093/ije/dyu001. View

15.

Behan L, Dimitrov B, Kuehni C, Hogg C, Carroll M, Evans H . PICADAR: a diagnostic predictive tool for primary ciliary dyskinesia. Eur Respir J. 2016; 47(4):1103-12. PMC: 4819882. DOI: 10.1183/13993003.01551-2015. View

16.

Collins J, Lithopoulos M, Santos C, Issa N, Mobius M, Ito C . Impaired Angiogenic Supportive Capacity and Altered Gene Expression Profile of Resident CD146 Mesenchymal Stromal Cells Isolated from Hyperoxia-Injured Neonatal Rat Lungs. Stem Cells Dev. 2018; 27(16):1109-1124. DOI: 10.1089/scd.2017.0145. View

17.

Garcia E, Zhang Y, Rappaport E, Berhane K, Muchmore P, Silkoff P . Patterns and determinants of exhaled nitric oxide trajectories in schoolchildren over a 7-year period. Eur Respir J. 2020; 56(1). PMC: 7335353. DOI: 10.1183/13993003.00011-2020. View

18.

Marthin J, Philipsen M, Rosthoj S, Nielsen K . Infant nasal nitric oxide over time: natural evolution and impact of respiratory tract infection. Eur Respir J. 2018; 51(6). DOI: 10.1183/13993003.02503-2017. View

19.

Ballard H, Shook L, Bernard P, Anstead M, Kuhn R, Whitehead V . Use of azithromycin for the prevention of bronchopulmonary dysplasia in preterm infants: a randomized, double-blind, placebo controlled trial. Pediatr Pulmonol. 2010; 46(2):111-8. DOI: 10.1002/ppul.21352. View

20.

Davis S, Rosenfeld M, Lee H, Ferkol T, Sagel S, Dell S . Primary Ciliary Dyskinesia: Longitudinal Study of Lung Disease by Ultrastructure Defect and Genotype. Am J Respir Crit Care Med. 2018; 199(2):190-198. PMC: 6353004. DOI: 10.1164/rccm.201803-0548OC. View