Nanotechnology in Metastatic Cancer Treatment: Current Achievements and Future Research Trends

Overview

Journal J Cancer

Specialty Oncology

Date 2019 Apr 30

PMID 31031845

Citations 9

Authors

Diana Gonciar

Teodora Mocan

Cristian Tudor Matea

Claudiu Zdrehus

Ofelia Mosteanu

Lucian Mocan

Teodora Pop

Affiliations

Soon will be listed here.

Abstract

The systemic spread of malignant cells from a primary site, a process termed metastasis represents a global challenge in cancer treatment. There is a real need to develop novel therapy strategies and nanomedicine may have remarkable and valuable contribution through specific and selective delivery of chemotherapeutic agents, through its intrinsic cytotoxic activity or through imaging applications, appealing also in the context of cancer personalized therapy. This review is focused on the applications of nanoparticles in the treatment of metastatic cancer, particularly on the possible effect on cell stabilization, growth inhibition, eventual interaction with adhesion molecules and antiangiogenic effect.

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