Molecular Survey of Species in Shelter Cats in Rio De Janeiro: Clinical, Hematological, and Risk Factors

Overview

Journal Am J Trop Med Hyg

Specialty Tropical Medicine

Date 2019 Apr 25

PMID 31017080

Citations 6

Authors

Juliana M Raimundo

Andresa Guimaraes

Gleice M Amaro

Aline T da Silva

Camila F M Botelho

Carlos L Massard

Elba R S de Lemos

Alexsandra R M Favacho

Cristiane D Baldani

Affiliations

Soon will be listed here.

Abstract

The present study aimed to detect DNA in cats belonging to shelters, and to evaluate risk factors, clinical signs, and hematological abnormalities associated with infection. Complete blood counts and screening for the presence of DNA were performed on cats' ethylenediamine tetraacetic acid anticoagulant-blood samples. Eighty-three cats (39.9%) were positive for species. DNA was also detected in fleas and in the blood of cats infested by positive flea. Cats that had not been sterilized, had outdoor access, had histories of fights, and had concurrent flea infestation were more likely to be infected by species ( < 0.05). Age and sex were not associated with infection. Fifty-one (38.6%) symptomatic cats were positive to species ( > 0.05). Clinical conditions most commonly observed were signs of respiratory abnormality and S species coinfection ( > 0.05). Regarding hematological changes, eosinophilia was associated with infection ( < 0.05). A high frequency of species infection was found in shelter cats and highlights the importance of adequate flea-control programs to prevent infection in cats and consequently in adopters and other animals.

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References

Miceli N, Gavioli F, Goncalves L, Andre M, Sousa V, de Sousa K . Molecular detection of feline arthropod-borne pathogens in cats in Cuiabá, state of Mato Grosso, central-western region of Brazil. Rev Bras Parasitol Vet. 2013; 22(3):385-90. DOI: 10.1590/S1984-29612013000300011. View

Breitschwerdt E, Broadhurst J, Cherry N . as a cause of acute-onset febrile illness in cats. JFMS Open Rep. 2017; 1(2):2055116915600454. PMC: 5362002. DOI: 10.1177/2055116915600454. View

Guptill L . Bartonellosis. Vet Microbiol. 2009; 140(3-4):347-59. DOI: 10.1016/j.vetmic.2009.11.011. View

Tsai Y, Lin C, Chomel B, Chuang S, Tsai K, Wu W . Bartonella infection in shelter cats and dogs and their ectoparasites. Vector Borne Zoonotic Dis. 2010; 11(8):1023-30. DOI: 10.1089/vbz.2010.0085. View

Mostl K, Egberink H, Addie D, Frymus T, Boucraut-Baralon C, Truyen U . Prevention of infectious diseases in cat shelters: ABCD guidelines. J Feline Med Surg. 2013; 15(7):546-54. PMC: 11148948. DOI: 10.1177/1098612X13489210. View

Kim Y, Seo K, Lee J, Choi E, Lee H, Hwang C . Prevalence of Bartonella henselae and Bartonella clarridgeiae in cats and dogs in Korea. J Vet Sci. 2009; 10(1):85-7. PMC: 2801096. DOI: 10.4142/jvs.2009.10.1.85. View

Andre M, Herrera H, Fernandes S, de Sousa K, Goncalves L, Domingos I . Tick-borne agents in domesticated and stray cats from the city of Campo Grande, state of Mato Grosso do Sul, midwestern Brazil. Ticks Tick Borne Dis. 2015; 6(6):779-86. DOI: 10.1016/j.ttbdis.2015.07.004. View

Abbott R, Chomel B, Kasten R, Kikuchi Y, Koehler J, Pedersen N . Experimental and natural infection with Bartonella henselae in domestic cats. Comp Immunol Microbiol Infect Dis. 1997; 20(1):41-51. DOI: 10.1016/s0147-9571(96)00025-2. View

Oskouizadeh K, Zahraei-Salehi T, Aledavood S . Detection of Bartonella henselae in domestic cats' saliva. Iran J Microbiol. 2012; 2(2):80-4. PMC: 3279777. View

10.

Stutzer B, Hartmann K . Chronic Bartonellosis in cats: what are the potential implications?. J Feline Med Surg. 2012; 14(9):612-21. PMC: 10822232. DOI: 10.1177/1098612X12458208. View

11.

Breitschwerdt E . Feline bartonellosis and cat scratch disease. Vet Immunol Immunopathol. 2008; 123(1-2):167-71. DOI: 10.1016/j.vetimm.2008.01.025. View

12.

Norman A, Regnery R, JAMESON P, Greene C, Krause D . Differentiation of Bartonella-like isolates at the species level by PCR-restriction fragment length polymorphism in the citrate synthase gene. J Clin Microbiol. 1995; 33(7):1797-803. PMC: 228273. DOI: 10.1128/jcm.33.7.1797-1803.1995. View

13.

Souza A, Almosny N, Favacho A, Almeida D, Ferreira R, Ferreira E . Bartonella spp. and hematological changes in privately owned domestic cats from Rio de Janeiro, Brazil. J Infect Dev Ctries. 2019; 11(8):591-596. DOI: 10.3855/jidc.8152. View

14.

Fleischman D, Chomel B, Kasten R, Stuckey M, Scarlet J, Liu H . Bartonella Infection among Cats Adopted from a San Francisco Shelter, Revisited. Appl Environ Microbiol. 2015; 81(18):6446-50. PMC: 4542261. DOI: 10.1128/AEM.01864-15. View

15.

Sanguinetti-Morelli D, Angelakis E, Richet H, Davoust B, Rolain J, Raoult D . Seasonality of cat-scratch disease, France, 1999-2009. Emerg Infect Dis. 2011; 17(4):705-7. PMC: 3377394. DOI: 10.3201/eid1704.100825. View

16.

Kordick D, Brown T, Shin K, Breitschwerdt E . Clinical and pathologic evaluation of chronic Bartonella henselae or Bartonella clarridgeiae infection in cats. J Clin Microbiol. 1999; 37(5):1536-47. PMC: 84823. DOI: 10.1128/JCM.37.5.1536-1547.1999. View

17.

Bergmans A, de Jong C, van Amerongen G, Schot C, Schouls L . Prevalence of Bartonella species in domestic cats in The Netherlands. J Clin Microbiol. 1997; 35(9):2256-61. PMC: 229949. DOI: 10.1128/jcm.35.9.2256-2261.1997. View

18.

Leibovitz K, Pearce L, Brewer M, Lappin M . Bartonella species antibodies and DNA in cerebral spinal fluid of cats with central nervous system disease. J Feline Med Surg. 2008; 10(4):332-7. PMC: 10832892. DOI: 10.1016/j.jfms.2007.12.011. View

19.

Horta M, Labruna M, Pinter A, Linardi P, Schumaker T . Rickettsia infection in five areas of the state of São Paulo, Brazil. Mem Inst Oswaldo Cruz. 2007; 102(7):793-801. DOI: 10.1590/s0074-02762007000700003. View

20.

Guptill L, Wu C, HogenEsch H, Slater L, GLICKMAN N, Dunham A . Prevalence, risk factors, and genetic diversity of Bartonella henselae infections in pet cats in four regions of the United States. J Clin Microbiol. 2004; 42(2):652-9. PMC: 344466. DOI: 10.1128/JCM.42.2.652-659.2004. View