» Articles » PMID: 31016909

Endophthalmitis After Cataract Surgery in Korea: A Nationwide Study Evaluating Incidence and Risk Factors in a Korean Population

Overview
Journal Yonsei Med J
Specialty General Medicine
Date 2019 Apr 25
PMID 31016909
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose: To assess the nationwide rate of acute postoperative endophthalmitis (APE) after cataract extraction in Korea and to evaluate potential risk factors thereof.

Materials And Methods: Nationwide insurance claims data from July 2014 to June 2017 were reviewed. All patients with phacoemulsification or extracapsular/intracapsular cataract extraction were included. Exclusion criteria were combined glaucoma surgery or total vitrectomy or when the patient had a history of intraocular foreign body.

Results: In total, 1505103 cases (982203 patients) were included. APE developed in 953 cases (938 patients) with an overall incidence of 0.063%. After adjusting for possible confounding factors, male sex [odds ratio (OR) 1.42; 95% confidence interval (CI) 1.25-1.61; <0.001], primary clinical setting, operations performed in non-major cities, usage of sutures (OR 2.82; 95% CI 2.13-3.74; <0.001), anterior vitrectomy (OR 8.71; 95% CI 6.71-11.32; <0.001), aphakic cataract surgery (OR 1.52; 95% CI 1.03-2.22; =0.033), hypertension (OR 1.40; 95% CI 1.18-1.66; <0.001), diabetes (OR 1.59; 95% CI 1.31-1.93; <0.001), and chronic renal failure (OR 1.28; 95% CI 1.01-1.62; =0.039) were found to be related to APE development.

Conclusion: The incidence of APE after cataract extraction was consistent with reports from other studies. Additional research is needed to determine the relationship of newly found risk factors, such as hypertension, primary clinical setting, chronic renal failure, and usage of suturing, with APE development.

Citing Articles

Impact of Patient Characteristics and Surgery-Related Risk Factors on Endophthalmitis after Cataract surgery: A Meta-Analysis.

Zhang S, Xu J Ophthalmic Res. 2025; 68(1):117-136.

PMID: 39773547 PMC: 11844714. DOI: 10.1159/000543353.


New Approaches to Overcoming Antimicrobial Resistance in Endophthalmitis.

Garcia OFarrill N, Abi Karam M, Villegas V, Flynn Jr H, Grzybowski A, Schwartz S Pharmaceuticals (Basel). 2024; 17(3).

PMID: 38543107 PMC: 10974156. DOI: 10.3390/ph17030321.


The Royal College of Ophthalmologists' National Ophthalmology Database Study of Cataract Surgery: Report 13, monitoring post-cataract surgery endophthalmitis rates-the rule of X.

Buchan J, Norridge C, Low L, Shah V, Donachie P Eye (Lond). 2024; 38(7):1386-1389.

PMID: 38200322 PMC: 11076627. DOI: 10.1038/s41433-023-02917-x.


A survey of Asian Eye Institutions on perioperative antibiotic prophylaxis in cataract surgery.

Garg P, Khor W, Roy A, Tan D Int Ophthalmol. 2023; 43(11):4151-4162.

PMID: 37526782 PMC: 10520096. DOI: 10.1007/s10792-023-02816-w.


Acute postoperative endophthalmitis after cataract operation: result of early vitrectomy within 24 hours of presentation.

Iu L, Chan H, Li G, Ho M, Mak A, Wong P Eye (Lond). 2022; 37(11):2344-2350.

PMID: 36513854 PMC: 10366129. DOI: 10.1038/s41433-022-02347-1.


References
1.
Sugar A, Schertzer R . Clinical course of phacoemulsification wound burns. J Cataract Refract Surg. 1999; 25(5):688-92. DOI: 10.1016/s0886-3350(99)00021-8. View

2.
Lertsumitkul S, Myers P, ORourke M, Chandra J . Endophthalmitis in the western Sydney region: a case-control study. Clin Exp Ophthalmol. 2002; 29(6):400-5. DOI: 10.1046/j.1442-9071.2001.d01-20.x. View

3.
Montan P, Wejde G, Koranyi G, Rylander M . Prophylactic intracameral cefuroxime. Efficacy in preventing endophthalmitis after cataract surgery. J Cataract Refract Surg. 2002; 28(6):977-81. DOI: 10.1016/s0886-3350(01)01269-x. View

4.
Nagaki Y, Hayasaka S, Kadoi C, Matsumoto M, Yanagisawa S, Watanabe K . Bacterial endophthalmitis after small-incision cataract surgery. effect of incision placement and intraocular lens type. J Cataract Refract Surg. 2003; 29(1):20-6. DOI: 10.1016/s0886-3350(02)01483-9. View

5.
Li J, Morlet N, Semmens J, Gavin A, Ng J . Coding accuracy for endophthalmitis diagnosis and cataract procedures in Western Australia. The Endophthalmitis Population Study of Western Australia (EPSWA): second report. Ophthalmic Epidemiol. 2003; 10(2):133-45. DOI: 10.1076/opep.10.2.133.13898. View