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» Articles » PMID: 31013583

Antibacterial Activity and Mechanisms of Essential Oil from

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2019 Apr 25
PMID 31013583
Citations 64
Authors
Ze-Hua Li
Ming Cai
Yuan-Shuai Liu
Pei-Long Sun
Shao-Lei Luo
Affiliations
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Abstract

In this work, antibacterial activity of finger citron essential oil (FCEO, ) and its mechanism against food-borne bacteria were evaluated. A total of 28 components in the oil were identified by gas chromatography-mass spectrometry, in which limonene (45.36%), γ-terpinene (21.23%), and dodecanoic acid (7.52%) were three main components. For in vitro antibacterial tests, FCEO exhibited moderately antibacterial activity against common food-borne bacteria: , , and . It showed a better bactericidal effect on Gram-positive bacteria than Gram-negative. Mechanisms of the antibacterial action were investigated by observing changes of bacteria morphology according to scanning electron microscopy, time-kill analysis, and permeability of cell and membrane integrity. Morphology of tested bacteria was changed and damaged more seriously with increased concentration and exposure time of FCEO. FCEO showed a significant reduction effect on the growth rate of surviving bacteria and lead to lysis of the cell wall, intracellular ingredient leakage, and consequently, cell death.

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