Meal Timing, Aging, and Metabolic Health

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2019 Apr 21

PMID 31003407

Citations 40

Authors

Katharina Kessler

Olga Pivovarova-Ramich

Affiliations

Soon will be listed here.

Abstract

A growing body of evidence suggests that meal timing is an important factor for metabolic regulation and that the circadian clock tightly interacts with metabolic functions. The proper functioning of the circadian clock is critical for maintaining metabolic health. Therefore, chrononutrition, a novel discipline which investigates the relation between circadian rhythms, nutrition, and metabolism, has attracted increasing attention in recent years. Circadian rhythms are strongly affected by obesity, type 2 diabetes, and other dietary-induced metabolic diseases. With increasing age, the circadian system also undergoes significant changes which contribute to the dysregulation of metabolic rhythms. Metabolic diseases are a major health concern, particularly in light of a growing aging population, and effective approaches for their prevention and treatment are urgently needed. Recently, animal studies have impressively shown beneficial effects of several dietary patterns (e.g., caloric restriction or time-restricted feeding) on circadian rhythms and metabolic outcomes upon nutritional challenges. Whether these dietary patterns show the same beneficial effects in humans is, however, less well studied. As indicated by recent studies, dietary approaches might represent a promising, attractive, and easy-to-adapt strategy for the prevention and therapy of circadian and metabolic disturbances in humans of different age.

Citing Articles

Association of the Composite Dietary Antioxidant Index and Consumption Time with NAFLD: The U.S. National Health and Nutrition Examination Survey, 2017-2020.

Zhang K, Xu Y, Zhang N, Liang X, Zhang H, Liang H Nutrients. 2024; 16(20).

PMID: 39458550 PMC: 11514589. DOI: 10.3390/nu16203556.

Twenty-Four Hour Glucose Profiles and Glycemic Variability during Intermittent Religious Dry Fasting and Time-Restricted Eating in Subjects without Diabetes: A Preliminary Study.

Peters B, Pappe C, Koppold D, Schipp K, Arnrich B, Michalsen A Nutrients. 2024; 16(16).

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Older adults exercising ON TIME: protocol for a randomized controlled cross-over study to assess the effect of physical activity timing on insomnia severity.

Albalak G, Noordam R, van der Elst M, Kervezee L, Exadaktylos V, van Bodegom D Trials. 2024; 25(1):523.

PMID: 39103937 PMC: 11299269. DOI: 10.1186/s13063-024-08310-7.

Chrononutrition and Cardiometabolic Health: An Overview of Epidemiological Evidence and Key Future Research Directions.

Raji O, Kyeremah E, Sears D, St-Onge M, Makarem N Nutrients. 2024; 16(14).

PMID: 39064774 PMC: 11280377. DOI: 10.3390/nu16142332.

Effect of Meal-Timing on the Association of Unsaturated Fatty Acids with All-Cause and Cardiovascular Mortality among Adults: A Prospective Cohort Study with 10-Year Follow-Up.

Gao J, Li C, Chen H, Li Z, You F, Song W Nutrients. 2024; 16(13).

PMID: 38999822 PMC: 11242975. DOI: 10.3390/nu16132071.

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