Efficacy of Diphenyleneiodonium Chloride (DPIC) Against Diverse Plant Pathogens

Overview

Journal Mycobiology

Date 2019 Apr 20

PMID 31001452

Citations 1

Authors

Boknam Jung

Taiying Li

Sungyeon Ji

Jungkwan Lee

Affiliations

Soon will be listed here.

Abstract

Many of the fungicides and antibiotics currently available against plant pathogens are of limited use due to the emergence of resistant strains. In this study, we examined the effects of diphenyleneiodonium chloride (DPIC), an inhibitor of the superoxide producing enzyme NADPH oxidase, against fungal and bacterial plant pathogens. We found that DPIC inhibits fungal spore germination and bacterial cell proliferation. In addition, we demonstrated the potent antibacterial activity of DPIC using rice heads infected with the bacterial pathogen which causes bacterial panicle blight (BPB). We found that treatment with DPIC reduced BPB when applied during the initial flowering stage of the rice heads. These results suggest that DPIC could serve as a new and useful antimicrobial agent in agriculture.

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