Putting It All Together: Noninvasive Diagnosis of Fibrosis in Nonalcoholic Fatty Liver Disease in Adults and Children

Overview

Journal Clin Liver Dis (Hoboken)

Specialty Gastroenterology

Date 2019 Apr 18

PMID 30992977

Citations 5

Authors

Naim Alkhouri

Affiliations

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Citing Articles

Clinical profile, referral trends, and real-world application of vibration-controlled transient elastography in children with non-alcoholic fatty liver disease in Singapore.

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Liver fibrosis in children: a comprehensive review of mechanisms, diagnosis, and therapy.

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Relationship of Enhanced Liver Fibrosis Score with Pediatric Nonalcoholic Fatty Liver Disease Histology and Response to Vitamin E or Metformin.

Gawrieh S, Harlow K, Pike F, Yates K, Wilson L, Cummings O J Pediatr. 2021; 239:161-167.e5.

PMID: 34400208 PMC: 8922020. DOI: 10.1016/j.jpeds.2021.08.012.

Prediction and Staging of Hepatic Fibrosis in Children with Hepatitis C Virus: A Machine Learning Approach.

Barakat N, Barakat S, Ahmed N Healthc Inform Res. 2019; 25(3):173-181.

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Is There an Association of Vascular Disease and Atherosclerosis in Children and Adolescents With Obesity and Non-alcoholic Fatty Liver Disease?.

Karjoo S Front Pediatr. 2018; 6:345.

PMID: 30505829 PMC: 6250730. DOI: 10.3389/fped.2018.00345.

References

Schwimmer J, Deutsch R, Kahen T, Lavine J, Stanley C, Behling C . Prevalence of fatty liver in children and adolescents. Pediatrics. 2006; 118(4):1388-93. DOI: 10.1542/peds.2006-1212. View

Nobili V, Vizzutti F, Arena U, Abraldes J, Marra F, Pietrobattista A . Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis. Hepatology. 2008; 48(2):442-8. DOI: 10.1002/hep.22376. View

Nobili V, Parkes J, Bottazzo G, Marcellini M, Cross R, Newman D . Performance of ELF serum markers in predicting fibrosis stage in pediatric non-alcoholic fatty liver disease. Gastroenterology. 2008; 136(1):160-7. DOI: 10.1053/j.gastro.2008.09.013. View

Fitzpatrick E, Mitry R, Quaglia A, Hussain M, DeBruyne R, Dhawan A . Serum levels of CK18 M30 and leptin are useful predictors of steatohepatitis and fibrosis in paediatric NAFLD. J Pediatr Gastroenterol Nutr. 2010; 51(4):500-6. DOI: 10.1097/MPG.0b013e3181e376be. View

Williams C, Stengel J, Asike M, Torres D, Shaw J, Contreras M . Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology. 2010; 140(1):124-31. DOI: 10.1053/j.gastro.2010.09.038. View

Lebensztejn D, Wierzbicka A, Socha P, Pronicki M, Skiba E, Werpachowska I . Cytokeratin-18 and hyaluronic acid levels predict liver fibrosis in children with non-alcoholic fatty liver disease. Acta Biochim Pol. 2011; 58(4):563-6. View

Xanthakos S, Podberesky D, Serai S, Miles L, King E, Balistreri W . Use of magnetic resonance elastography to assess hepatic fibrosis in children with chronic liver disease. J Pediatr. 2013; 164(1):186-8. PMC: 3872246. DOI: 10.1016/j.jpeds.2013.07.050. View

Alkhouri N, Mansoor S, Giammaria P, Liccardo D, Lopez R, Nobili V . The development of the pediatric NAFLD fibrosis score (PNFS) to predict the presence of advanced fibrosis in children with nonalcoholic fatty liver disease. PLoS One. 2014; 9(8):e104558. PMC: 4133235. DOI: 10.1371/journal.pone.0104558. View

Ekstedt M, Hagstrom H, Nasr P, Fredrikson M, Stal P, Kechagias S . Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. Hepatology. 2014; 61(5):1547-54. DOI: 10.1002/hep.27368. View

10.

Mansoor S, Yerian L, Kohli R, Xanthakos S, Angulo P, Ling S . The evaluation of hepatic fibrosis scores in children with nonalcoholic fatty liver disease. Dig Dis Sci. 2014; 60(5):1440-7. DOI: 10.1007/s10620-014-3494-7. View

11.

Angulo P, Kleiner D, Dam-Larsen S, Adams L, Bjornsson E, Charatcharoenwitthaya P . Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2015; 149(2):389-97.e10. PMC: 4516664. DOI: 10.1053/j.gastro.2015.04.043. View

12.

Alkhouri N, Hanouneh I, Zein N, Lopez R, Kelly D, Eghtesad B . Liver transplantation for nonalcoholic steatohepatitis in young patients. Transpl Int. 2015; 29(4):418-24. DOI: 10.1111/tri.12694. View

13.

Mandelia C, Collyer E, Mansoor S, Lopez R, Lappe S, Nobili V . Plasma Cytokeratin-18 Level As a Novel Biomarker for Liver Fibrosis in Children With Nonalcoholic Fatty Liver Disease. J Pediatr Gastroenterol Nutr. 2016; 63(2):181-7. DOI: 10.1097/MPG.0000000000001136. View

14.

Alkhouri N, Feldstein A . Noninvasive diagnosis of nonalcoholic fatty liver disease: Are we there yet?. Metabolism. 2016; 65(8):1087-95. PMC: 4931968. DOI: 10.1016/j.metabol.2016.01.013. View