[Folic Acid and Vitamin B12 Determination in the Assessment of Cognitive Disorders : Overview and Data Analysis from a University Outpatient Memory Clinic]

Overview

Journal Nervenarzt

Specialty Neurology

Date 2019 Apr 11

PMID 30968196

Citations 2

Authors

Robert Haussmann

Cathrin Sauer

Stefanie Neumann

Anne Zweiniger

Jan Lange

Markus Donix

Affiliations

Soon will be listed here.

Abstract

Vitamin B12 and folic acid deficiencies are particularly frequent conditions in older people. Since these metabolic disorders represent relevant dyscognitive factors, the assessment of vitamin B12 and folic acid levels is essential in the diagnostic approach of cognitive disorders, such as mild cognitive impairment and dementia in an outpatient memory clinic. This article summarizes the relevant diagnostic and therapeutic aspects of vitamin B12 and folic acid deficiencies and their effects on cognition. The literature review is supplemented by a data analysis of a naturalistic cohort of 250 patients from this outpatient memory clinic.

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