Mycobacterial Evolution Intersects With Host Tolerance

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2019 Apr 11

PMID 30967867

Citations 19

Authors

Joseph W Saelens

Gopinath Viswanathan

David M Tobin

Affiliations

Soon will be listed here.

Abstract

Over the past 200 years, tuberculosis (TB) has caused more deaths than any other infectious disease, likely infecting more people than it has at any other time in human history. (), the etiologic agent of TB, is an obligate human pathogen that has evolved through the millennia to become an archetypal human-adapted pathogen. This review focuses on the evolutionary framework by which emerged as a specialized human pathogen and applies this perspective to the emergence of specific lineages that drive global TB burden. We consider how evolutionary pressures, including transmission dynamics, host tolerance, and human population patterns, may have shaped the evolution of diverse mycobacterial genomes.

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References

Tobin D, Roca F, Oh S, McFarland R, Vickery T, Ray J . Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell. 2012; 148(3):434-46. PMC: 3433720. DOI: 10.1016/j.cell.2011.12.023. View

Fishbein S, Wyk N, Warren R, Sampson S . Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity. Mol Microbiol. 2015; 96(5):901-16. DOI: 10.1111/mmi.12981. View

Sakamoto K, Kim M, Rhoades E, Allavena R, Ehrt S, Wainwright H . Mycobacterial trehalose dimycolate reprograms macrophage global gene expression and activates matrix metalloproteinases. Infect Immun. 2012; 81(3):764-76. PMC: 3584883. DOI: 10.1128/IAI.00906-12. View

Lewis K, Liao R, Guinn K, Hickey M, Smith S, Behr M . Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation. J Infect Dis. 2003; 187(1):117-23. PMC: 1458498. DOI: 10.1086/345862. View

Nigou J, Gilleron M, Thurnher M, Puzo G . Mannosylated lipoarabinomannans inhibit IL-12 production by human dendritic cells: evidence for a negative signal delivered through the mannose receptor. J Immunol. 2001; 166(12):7477-85. DOI: 10.4049/jimmunol.166.12.7477. View

Oehlers S, Cronan M, Scott N, Thomas M, Okuda K, Walton E . Interception of host angiogenic signalling limits mycobacterial growth. Nature. 2014; 517(7536):612-5. PMC: 4312197. DOI: 10.1038/nature13967. View

Allison M, Mendoza D, Pezzia A . Documentation of a case of tuberculosis in Pre-Columbian America. Am Rev Respir Dis. 1973; 107(6):985-91. DOI: 10.1164/arrd.1973.107.6.985. View

Chan J, Fujiwara T, Brennan P, McNeil M, Turco S, Sibille J . Microbial glycolipids: possible virulence factors that scavenge oxygen radicals. Proc Natl Acad Sci U S A. 1989; 86(7):2453-7. PMC: 286931. DOI: 10.1073/pnas.86.7.2453. View

Baker L, Brown T, Maiden M, Drobniewski F . Silent nucleotide polymorphisms and a phylogeny for Mycobacterium tuberculosis. Emerg Infect Dis. 2004; 10(9):1568-77. PMC: 3320301. DOI: 10.3201/eid1009.040046. View

10.

Comas I, Coscolla M, Luo T, Borrell S, Holt K, Kato-Maeda M . Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Nat Genet. 2013; 45(10):1176-82. PMC: 3800747. DOI: 10.1038/ng.2744. View

11.

Gutierrez M, Brisse S, Brosch R, Fabre M, Omais B, Marmiesse M . Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis. PLoS Pathog. 2005; 1(1):e5. PMC: 1238740. DOI: 10.1371/journal.ppat.0010005. View

12.

Lou Y, Rybniker J, Sala C, Cole S . EspC forms a filamentous structure in the cell envelope of Mycobacterium tuberculosis and impacts ESX-1 secretion. Mol Microbiol. 2016; 103(1):26-38. DOI: 10.1111/mmi.13575. View

13.

Nebenzahl-Guimaraes H, Verhagen L, Borgdorff M, van Soolingen D . Transmission and Progression to Disease of Mycobacterium tuberculosis Phylogenetic Lineages in The Netherlands. J Clin Microbiol. 2015; 53(10):3264-71. PMC: 4572527. DOI: 10.1128/JCM.01370-15. View

14.

Canueto-Quintero J, Caballero-Granado F, Herrero-Romero M, Dominguez-Castellano A, Martin-Rico P, Vidal Verdu E . Epidemiological, clinical, and prognostic differences between the diseases caused by Mycobacterium kansasii and Mycobacterium tuberculosis in patients infected with human immunodeficiency virus: a multicenter study. Clin Infect Dis. 2003; 37(4):584-90. DOI: 10.1086/376987. View

15.

Cambier C, Falkow S, Ramakrishnan L . Host evasion and exploitation schemes of Mycobacterium tuberculosis. Cell. 2014; 159(7):1497-509. DOI: 10.1016/j.cell.2014.11.024. View

16.

Brodin P, Majlessi L, Marsollier L, de Jonge M, Bottai D, Demangel C . Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. Infect Immun. 2005; 74(1):88-98. PMC: 1346617. DOI: 10.1128/IAI.74.1.88-98.2006. View

17.

Rao V, Fujiwara N, Porcelli S, Glickman M . Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule. J Exp Med. 2005; 201(4):535-43. PMC: 2213067. DOI: 10.1084/jem.20041668. View

18.

Manca C, Tsenova L, Barry 3rd C, Bergtold A, Freeman S, Haslett P . Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates. J Immunol. 1999; 162(11):6740-6. View

19.

Siegrist M, Steigedal M, Ahmad R, Mehra A, Dragset M, Schuster B . Mycobacterial Esx-3 requires multiple components for iron acquisition. mBio. 2014; 5(3):e01073-14. PMC: 4010830. DOI: 10.1128/mBio.01073-14. View

20.

Houben R, Dodd P . The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling. PLoS Med. 2016; 13(10):e1002152. PMC: 5079585. DOI: 10.1371/journal.pmed.1002152. View