Fatal Necrotizing Esophagitis in a Patient with Leukocytoclastic Cutaneous Vasculitis and Ankylosing Spondylitis

Overview

Journal Autops Case Rep

Date 2019 Apr 10

PMID 30963052

Citations 5

Authors

Mario Luiz Marques Piubelli

Aloisio Felipe-Silva

Marcia Yoshie Kanegae

Fernando Peixoto Ferraz de Campos

Affiliations

Soon will be listed here.

Abstract

Esophageal infection by spp. is a common opportunistic entity in immunocompromised hosts; however, systemic fungal dissemination due to perforation or transmural necrosis, also known as necrotizing esophagitis (NCE), is rare. We report the case of a 61-year-old male patient with diagnosed ankylosing spondylitis, severe arteriosclerosis, and vasculitis under immunosuppressive therapy who presented NCE with fungal and bacterial septicemia diagnosed at autopsy. Necrotizing esophagitis is a rare manifestation of infection, which may be a final complication in severely ill patients. Unfortunately, it may be underdiagnosed, and we call attention to this devastating complication in patients with leukocytoclastic cutaneous vasculitis and ankylosing spondylitis.

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