Ultrasonography for Oxygen-ozone Therapy in Musculoskeletal Diseases

Overview

Journal Med Gas Res

Specialties Anesthesiology
General Medicine
Pharmacology

Date 2019 Apr 6

PMID 30950416

Citations 7

Authors

Eleonora Latini

Enrico Roberto Curci

Andrea Massimiani

Sveva Maria Nusca

Flavia Santoboni

Donatella Trischitta

Mario Vetrano

Maria Chiara Vulpiani

Affiliations

Soon will be listed here.

Abstract

Over the years, infiltrative oxygen-ozone therapy has shown clinical benefits in several musculoskeletal disorders, due to its potential analgesic, anti-inflammatory, antioxidant and immunomodulatory effect. Ultrasonography is a safe, non-invasive imaging, easily available, and has the additional advantage of being real time for imaging and image-guided procedures of the musculoskeletal system. This review explains the numerous promising ways in which ultrasonography can be useful in oxygen-ozone therapeutic practices for musculoskeletal disorders, in order to improve safety and accuracy of treatment.

Citing Articles

Ozone infiltration as an adjunctive treatment to piezoelectric surgery in the management of medication-related osteonecrosis of the jaws: case series of 29 patients.

Goker F, Donati G, Gallo F, Sparaco A, Rania V, Busa A Oral Maxillofac Surg. 2024; 28(3):1197-1207.

PMID: 38523198 DOI: 10.1007/s10006-024-01246-x.

Intramuscular paravertebral oxygen-ozone therapy for chronic neck pain and low back pain: evaluation of 6-month clinical outcomes.

Latini E, Nusca S, Curci E, Boaretto D, Santoboni F, Trischitta D Med Gas Res. 2023; 14(1):6-11.

PMID: 37721249 PMC: 10710283. DOI: 10.4103/2045-9912.374388.

Ozone Infiltration for Osteonecrosis of the Jaw Therapy: A Case Series.

Di Fede O, Del Gaizo C, Panzarella V, La Mantia G, Tozzo P, Di Grigoli A J Clin Med. 2022; 11(18).

PMID: 36142954 PMC: 9502994. DOI: 10.3390/jcm11185307.

Oxygen-Ozone Therapy in the Rehabilitation Field: State of the Art on Mechanisms of Action, Safety and Effectiveness in Patients with Musculoskeletal Disorders.

de Sire A, Agostini F, Lippi L, Mangone M, Marchese S, Cisari C Biomolecules. 2021; 11(3).

PMID: 33652804 PMC: 7996934. DOI: 10.3390/biom11030356.

Integration of focal vibration and intra-articular oxygen-ozone therapy in rehabilitation of painful knee osteoarthritis.

Paolucci T, Agostini F, Bernetti A, Paoloni M, Mangone M, Santilli V J Int Med Res. 2021; 49(2):300060520986705.

PMID: 33641438 PMC: 7923992. DOI: 10.1177/0300060520986705.

References

Naredo E, Cabero F, Beneyto P, Cruz A, Mondejar B, Uson J . A randomized comparative study of short term response to blind injection versus sonographic-guided injection of local corticosteroids in patients with painful shoulder. J Rheumatol. 2004; 31(2):308-14. View

Stokes M, Rankin G, Newham D . Ultrasound imaging of lumbar multifidus muscle: normal reference ranges for measurements and practical guidance on the technique. Man Ther. 2005; 10(2):116-26. DOI: 10.1016/j.math.2004.08.013. View

Calabrese E . Paradigm lost, paradigm found: the re-emergence of hormesis as a fundamental dose response model in the toxicological sciences. Environ Pollut. 2005; 138(3):379-411. DOI: 10.1016/j.envpol.2004.10.001. View

Bocci V . Scientific and medical aspects of ozone therapy. State of the art. Arch Med Res. 2006; 37(4):425-35. DOI: 10.1016/j.arcmed.2005.08.006. View

Bron J, van Royen B, Wuisman P . The clinical significance of lumbosacral transitional anomalies. Acta Orthop Belg. 2008; 73(6):687-95. View

Al-Jaziri A, Mahmoodi S . Painkilling effect of ozone-oxygen injection on spine and joint osteoarthritis. Saudi Med J. 2008; 29(4):553-7. View

Luz K, Furtado R, Nunes C, Rosenfeld A, Fernandes A, Natour J . Ultrasound-guided intra-articular injections in the wrist in patients with rheumatoid arthritis: a double-blind, randomised controlled study. Ann Rheum Dis. 2008; 67(8):1198-200. DOI: 10.1136/ard.2007.084616. View

Louis L . Musculoskeletal ultrasound intervention: principles and advances. Radiol Clin North Am. 2008; 46(3):515-33, vi. DOI: 10.1016/j.rcl.2008.02.003. View

Bocci V, Borrelli E, Travagli V, Zanardi I . The ozone paradox: ozone is a strong oxidant as well as a medical drug. Med Res Rev. 2009; 29(4):646-82. DOI: 10.1002/med.20150. View

10.

Smith J, Finnoff J . Diagnostic and interventional musculoskeletal ultrasound: part 2. Clinical applications. PM R. 2009; 1(2):162-77. DOI: 10.1016/j.pmrj.2008.09.002. View

11.

Sibbitt Jr W, Peisajovich A, Michael A, Park K, Sibbitt R, Band P . Does sonographic needle guidance affect the clinical outcome of intraarticular injections?. J Rheumatol. 2009; 36(9):1892-902. DOI: 10.3899/jrheum.090013. View

12.

Pysyk C, Persaud D, Bryson G, Lui A . Ultrasound assessment of the vertebral level of the palpated intercristal (Tuffier's) line. Can J Anaesth. 2009; 57(1):46-9. DOI: 10.1007/s12630-009-9208-5. View

13.

Smith J, Finnoff J, Santaella-Sante B, Henning T, Levy B, Lai J . Sonographically guided popliteus tendon sheath injection: techniques and accuracy. J Ultrasound Med. 2010; 29(5):775-82. DOI: 10.7863/jum.2010.29.5.775. View

14.

Chin K, Karmakar M, Peng P . Ultrasonography of the adult thoracic and lumbar spine for central neuraxial blockade. Anesthesiology. 2011; 114(6):1459-85. DOI: 10.1097/ALN.0b013e318210f9f8. View

15.

Royall N, Farrin E, Bahner D, Stawicki S . Ultrasound-assisted musculoskeletal procedures: A practical overview of current literature. World J Orthop. 2012; 2(7):57-66. PMC: 3302042. DOI: 10.5312/wjo.v2.i7.. View

16.

Bocci V . How a calculated oxidative stress can yield multiple therapeutic effects. Free Radic Res. 2012; 46(9):1068-75. DOI: 10.3109/10715762.2012.693609. View

17.

Bocci V, Valacchi G . Free radicals and antioxidants: how to reestablish redox homeostasis in chronic diseases?. Curr Med Chem. 2013; 20(27):3397-415. DOI: 10.2174/0929867311320270005. View

18.

Oh C, Ji G, Yoon S, Hyun D, Choi C, Lim H . Surface Landmarks do not Correspond to Exact Levels of the Cervical Spine: References According to the Sex, Age and Height. Korean J Spine. 2014; 11(3):178-82. PMC: 4206974. DOI: 10.14245/kjs.2014.11.3.178. View

19.

Perri M, Grattacaso G, Di Tunno V, Marsecano C, Gennarelli A, Michelini G . T2 shine-through phenomena in diffusion-weighted MR imaging of lumbar discs after oxygen-ozone discolysis: a randomized, double-blind trial with steroid and O2-O3 discolysis versus steroid only. Radiol Med. 2015; 120(10):941-50. DOI: 10.1007/s11547-015-0519-z. View

20.

Bocci V, Borrelli E, Zanardi I, Travagli V . The usefulness of ozone treatment in spinal pain. Drug Des Devel Ther. 2015; 9:2677-85. PMC: 4440430. DOI: 10.2147/DDDT.S74518. View