CT Characterisation of Feline Adrenal Glands

Overview

Journal J Feline Med Surg

Specialty Veterinary Medicine

Date 2019 Apr 4

PMID 30942657

Citations 4

Authors

Claudia Mallol

Raul Altuzarra

Yvonne Espada

Mauricio Tobon Restrepo

Emmanuel Serrano

Rosa Novellas

Affiliations

Soon will be listed here.

Abstract

Objectives: The objectives of this study were to describe the CT characteristics of the adrenal glands in healthy cats, to provide normal reference biometry for adrenal gland size and attenuation values, and to investigate the association with age, sex, laterality and body weight.

Methods: Retrospective evaluation of 30 CT studies of healthy adult cats recruited from September 2013 to July 2015 was performed. Healthy cats >1 year of age were included based on the absence of clinical signs, unremarkable physical examination, normal results of the complete blood count, biochemical profile, feline immunodeficiency virus, feline leukaemia virus and species infection tests. The relationship between gland biometry (size and attenuation values) and the age, sex, laterality and body weight of cats were tested by two-way ANOVA. The intraclass correlation coefficient was assessed and mean, SD, range provided.

Results: Twenty-seven cats were included. Bilobed, arrowhead and oval adrenal gland shape patterns were recognised, the first being most common. No statistically significant differences were observed between the biometric parameters (length, height and attenuation values) and age, sex, Regarding the width of the adrenal glands, there was a statistically significant effect of sex and laterality. he length (11.6 ± 2.1 mm) and height (6.1 ± 1.3 mm) were the most consistent biometrical parameters to describe adrenal glands.

Conclusions And Relevance: Adrenal gland shape, size and attenuation CT data of healthy feline patients are provided in this study, as well as normal reference intervals for morphometric characterisation based on adrenal length and height.

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References

Soulsby S, Holland M, Hudson J, Behrend E . Ultrasonographic evaluation of adrenal gland size compared to body weight in normal dogs. Vet Radiol Ultrasound. 2014; 56(3):317-26. DOI: 10.1111/vru.12236. View

Ross M, GAINER J, Innes J . Dystrophic calcification in the adrenal glands of monkeys, cats, and dogs. AMA Arch Pathol. 1955; 60(6):655-62. View

TICER J . Roentgen signs of endocrine disease. Vet Clin North Am. 1977; 7(3):465-86. DOI: 10.1016/s0091-0279(77)50053-6. View

Bertolini G, Furlanello T, De Lorenzi D, Caldin M . Computed tomographic quantification of canine adrenal gland volume and attenuation. Vet Radiol Ultrasound. 2006; 47(5):444-8. DOI: 10.1111/j.1740-8261.2006.00164.x. View

Valentin S, Cortright C, Nelson R, Pressler B, Rosenberg D, Moore G . Clinical findings, diagnostic test results, and treatment outcome in cats with spontaneous hyperadrenocorticism: 30 cases. J Vet Intern Med. 2014; 28(2):481-7. PMC: 4858028. DOI: 10.1111/jvim.12298. View

Westropp J, Welk K, Buffington C . Small adrenal glands in cats with feline interstitial cystitis. J Urol. 2003; 170(6 Pt 1):2494-7. DOI: 10.1097/01.ju.0000095566.63870.66. View

Zatelli A, DIppolito P, Fiore I, Zini E . Ultrasonographic evaluation of the size of the adrenal glands of 24 diseased cats without endocrinopathies. Vet Rec. 2007; 160(19):658-60. DOI: 10.1136/vr.160.19.658. View

Gregori T, Mantis P, Benigni L, Priestnall S, Lamb C . Comparison of computed tomographic and pathologic findings in 17 dogs with primary adrenal neoplasia. Vet Radiol Ultrasound. 2014; 56(2):153-9. DOI: 10.1111/vru.12209. View

Hoenig M . Feline hyperadrenocorticism--where are we now?. J Feline Med Surg. 2002; 4(3):171-4. PMC: 10822568. DOI: 10.1053/jfms.2002.0178. View

10.

Zimmer C, Horauf A, Reusch C . Ultrasonographic examination of the adrenal gland and evaluation of the hypophyseal-adrenal axis in 20 cats. J Small Anim Pract. 2000; 41(4):156-60. DOI: 10.1111/j.1748-5827.2000.tb03185.x. View

11.

Marine D . CALCIFICATION OF THE SUPRARENAL GLANDS OF CATS. J Exp Med. 2009; 43(4):495-9. PMC: 2131119. DOI: 10.1084/jem.43.4.495. View

12.

Combes A, Pey P, Paepe D, Rosenberg D, Daminet S, Putcuyps I . Ultrasonographic appearance of adrenal glands in healthy and sick cats. J Feline Med Surg. 2012; 15(6):445-57. PMC: 10816315. DOI: 10.1177/1098612X12469523. View

13.

Emms S, Wortman J, Johnston D, Goldschmidt M . Evaluation of canine hyperadrenocorticism, using computed tomography. J Am Vet Med Assoc. 1986; 189(4):432-9. View

14.

Groell R, Machan L, Schaffler G, Uggowitzer M, Peichel K . Morphometric measurement of abdominal organs. Comparison of ultrasound and spiral CT. Acta Radiol. 1997; 38(6):982-5. DOI: 10.1080/02841859709172114. View

15.

Ash R, Harvey A, Tasker S . Primary hyperaldosteronism in the cat: a series of 13 cases. J Feline Med Surg. 2005; 7(3):173-82. PMC: 10832728. DOI: 10.1016/j.jfms.2004.08.007. View

16.

BERGMAN S, Scouras G . Incidental bilateral adrenal calcification. Urology. 1983; 22(6):665-6. DOI: 10.1016/0090-4295(83)90324-2. View

17.

Bartko J . The intraclass correlation coefficient as a measure of reliability. Psychol Rep. 1966; 19(1):3-11. DOI: 10.2466/pr0.1966.19.1.3. View

18.

Combes A, Vandermeulen E, Duchateau L, Peremans K, Daminet S, Saunders J . Ultrasonographic measurements of adrenal glands in cats with hyperthyroidism. Vet Radiol Ultrasound. 2011; 53(2):210-6. DOI: 10.1111/j.1740-8261.2011.01888.x. View

19.

Voorhout G . X-ray-computed tomography, nephrotomography, and ultrasonography of the adrenal glands of healthy dogs. Am J Vet Res. 1990; 51(4):625-31. View

20.

Widmer W, Guptill L . Imaging techniques for facilitating diagnosis of hyperadrenocorticism in dogs and cats. J Am Vet Med Assoc. 1995; 206(12):1857-64. View