Discovery of Teneurins

Overview

Journal Front Neurosci

Date 2019 Apr 4

PMID 30941006

Citations 8

Authors

Stefan Baumgartner

Ron Wides

Affiliations

Soon will be listed here.

Abstract

Teneurins were first discovered and published in 1993 and 1994, in as and They were initially described as cell surface proteins, and as pair-rule genes. Later, they proved to be type II transmembrane proteins, and not to be pair-rule genes. might nonetheless have had an ancestral function in clock-based segmentation as a Ten-m oscillator. The turn of the millennium saw a watershed of vertebrate Teneurin discovery, which was soon complemented by Teneurin protein annotations from whole genome sequence publications. Teneurins encode proteins with essentially invariant domain order and size. The first years of Teneurin studies in many experimental systems led to key insights, and a unified picture, of Teneurin proteins.

Citing Articles

Striped Expression of Leucine-Rich Repeat Proteins Coordinates Cell Intercalation and Compartment Boundary Formation in the Early Embryo.

Kuebler C, Pare A Symmetry (Basel). 2024; 15(8).

PMID: 38650964 PMC: 11034934. DOI: 10.3390/sym15081490.

The structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers.

Li J, Bandekar S, Arac D EMBO Rep. 2023; 24(6):e56728.

PMID: 37165720 PMC: 10240212. DOI: 10.15252/embr.202256728.

Teneurin and TCAP Phylogeny and Physiology: Molecular Analysis, Immune Activity, and Transcriptomic Analysis of the Stress Response in the Sydney Rock Oyster () Hemocytes.

Abramov T, Suwansa-Ard S, Mirella da Silva P, Wang T, Dove M, OConnor W Front Endocrinol (Lausanne). 2022; 13:891714.

PMID: 35784537 PMC: 9248207. DOI: 10.3389/fendo.2022.891714.

Signaling Pathways Regulating the Expression of the Glioblastoma Invasion Factor .

Carcelen M, Velasquez C, Vidal V, Gutierrez O, Fernandez-Luna J Biomedicines. 2022; 10(5).

PMID: 35625843 PMC: 9138594. DOI: 10.3390/biomedicines10051104.

Role of Teneurin C-Terminal Associated Peptides (TCAP) on Intercellular Adhesion and Communication.

Dodsworth T, Lovejoy D Front Neurosci. 2022; 16:868541.

PMID: 35585927 PMC: 9108700. DOI: 10.3389/fnins.2022.868541.

References

Oohashi T, Zhou X, Feng K, Richter B, Morgelin M, Perez M . Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues. J Cell Biol. 1999; 145(3):563-77. PMC: 2185078. DOI: 10.1083/jcb.145.3.563. View

Ben-Zur T, Wides R . Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25. Genomics. 1999; 58(1):102-3. DOI: 10.1006/geno.1999.5798. View

Minet A, Rubin B, Tucker R, Baumgartner S, Chiquet-Ehrismann R . Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. J Cell Sci. 1999; 112 ( Pt 12):2019-32. DOI: 10.1242/jcs.112.12.2019. View

Otaki J, Firestein S . Neurestin: putative transmembrane molecule implicated in neuronal development. Dev Biol. 1999; 212(1):165-81. DOI: 10.1006/dbio.1999.9310. View

Mieda M, Kikuchi Y, Hirate Y, Aoki M, Okamoto H . Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila ten(m)/odd Oz gene, in the central nervous system. Mech Dev. 1999; 87(1-2):223-7. DOI: 10.1016/s0925-4773(99)00155-0. View

Wang X, Jolicoeur E, Conte N, Chaffanet M, Zhang Y, Mozziconacci M . gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line. Oncogene. 1999; 18(41):5718-21. DOI: 10.1038/sj.onc.1202950. View

Otaki J, Firestein S . Segregated expression of neurestin in the developing olfactory bulb. Neuroreport. 1999; 10(12):2677-80. DOI: 10.1097/00001756-199908200-00044. View

Rubin B, Tucker R, Martin D, Chiquet-Ehrismann R . Teneurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene product Ten-m. Dev Biol. 1999; 216(1):195-209. DOI: 10.1006/dbio.1999.9503. View

Ben-Zur T, Feige E, Motro B, Wides R . The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles. Dev Biol. 2000; 217(1):107-20. DOI: 10.1006/dbio.1999.9532. View

10.

Brown M, Ye J, Rawson R, Goldstein J . Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell. 2000; 100(4):391-8. DOI: 10.1016/s0092-8674(00)80675-3. View

11.

Adams M, Celniker S, Holt R, Evans C, Gocayne J, Amanatides P . The genome sequence of Drosophila melanogaster. Science. 2000; 287(5461):2185-95. DOI: 10.1126/science.287.5461.2185. View

12.

Minet A, Chiquet-Ehrismann R . Phylogenetic analysis of teneurin genes and comparison to the rearrangement hot spot elements of E. coli. Gene. 2000; 257(1):87-97. DOI: 10.1016/s0378-1119(00)00388-7. View

13.

. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature. 2000; 408(6814):796-815. DOI: 10.1038/35048692. View

14.

Venter J, Adams M, Myers E, Li P, Mural R, Sutton G . The sequence of the human genome. Science. 2001; 291(5507):1304-51. DOI: 10.1126/science.1058040. View

15.

Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J . Initial sequencing and analysis of the human genome. Nature. 2001; 409(6822):860-921. DOI: 10.1038/35057062. View

16.

Meinhardt H, de Boer P . Pattern formation in Escherichia coli: a model for the pole-to-pole oscillations of Min proteins and the localization of the division site. Proc Natl Acad Sci U S A. 2001; 98(25):14202-7. PMC: 64659. DOI: 10.1073/pnas.251216598. View

17.

Wood V, Gwilliam R, Rajandream M, LYNE M, Lyne R, Stewart A . The genome sequence of Schizosaccharomyces pombe. Nature. 2002; 415(6874):871-80. DOI: 10.1038/nature724. View

18.

Yu J, Hu S, Wang J, Wong G, Li S, Liu B . A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science. 2002; 296(5565):79-92. DOI: 10.1126/science.1068037. View

19.

Goff S, Ricke D, Lan T, Presting G, Wang R, Dunn M . A draft sequence of the rice genome (Oryza sativa L. ssp. japonica). Science. 2002; 296(5565):92-100. DOI: 10.1126/science.1068275. View

20.

Feng K, Zhou X, Oohashi T, Morgelin M, Lustig A, Hirakawa S . All four members of the Ten-m/Odz family of transmembrane proteins form dimers. J Biol Chem. 2002; 277(29):26128-35. DOI: 10.1074/jbc.M203722200. View