» Articles » PMID: 30937075

Pediatric Tubercular Meningitis: A Review

Overview
Specialty Pediatrics
Date 2019 Apr 3
PMID 30937075
Citations 9
Authors
Affiliations
Soon will be listed here.
Abstract

Childhood tuberculosis (TB) has a high incidence and prevalence in developing countries like India with tubercular meningitis (TBM) being the most common cause of death. Most cases of TBM are diagnosed late when despite adequate therapy; morbidity and mortality continue to remain high. This review aims to provide a pragmatic approach at dealing with cases of tubercular meningitis in children including clinical features, laboratory and radiological criteria, treatment options and prognostic implications. The objective of this review is to assist in early identification, proper investigation and timely treatment of TBM in children in order to reduce neurological morbidity and mortality associated with it.

Citing Articles

Tuberculosis Meningitis in a 9-Month-Old Girl during the COVID-19 Pandemic.

Bordbari A, Sheidaee K, Hajialibeig A, Navaeifar M, Gooran M, Rezai M Case Rep Med. 2024; 2024:9586953.

PMID: 39345734 PMC: 11436272. DOI: 10.1155/2024/9586953.


Factors associated with in-hospital mortality in HIV-infected children treated for tuberculous meningitis hydrocephalus.

Enicker B, Aldous C Childs Nerv Syst. 2023; 40(3):695-705.

PMID: 37964056 PMC: 10891234. DOI: 10.1007/s00381-023-06205-7.


Epstein-Barr virus meningoencephalitis in a young immunocompetent child: A case report.

Pangprasertkul S, Sanguansermsri C, Sudjaritruk T Heliyon. 2022; 8(10):e11150.

PMID: 36299527 PMC: 9589165. DOI: 10.1016/j.heliyon.2022.e11150.


Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?.

Maphalle L, Michniak-Kohn B, Ogunrombi M, Adeleke O Children (Basel). 2022; 9(8).

PMID: 36010011 PMC: 9406656. DOI: 10.3390/children9081120.


Tuberculous Meningitis in Children: Reducing the Burden of Death and Disability.

Huynh J, Abo Y, du Preez K, Solomons R, Dooley K, Seddon J Pathogens. 2022; 11(1).

PMID: 35055986 PMC: 8778027. DOI: 10.3390/pathogens11010038.


References
1.
Ozates M, Kemaloglu S, Gurkan F, Ozkan U, Hosoglu S, Simsek M . CT of the brain in tuberculous meningitis. A review of 289 patients. Acta Radiol. 2000; 41(1):13-7. DOI: 10.1034/j.1600-0455.2000.041001013.x. View

2.
Farinha N, Razali K, Holzel H, MORGAN G, Novelli V . Tuberculosis of the central nervous system in children: a 20-year survey. J Infect. 2000; 41(1):61-8. DOI: 10.1053/jinf.2000.0692. View

3.
Schoeman J, Wait J, Burger M, van Zyl F, Fertig G, van Rensburg A . Long-term follow up of childhood tuberculous meningitis. Dev Med Child Neurol. 2002; 44(8):522-6. DOI: 10.1017/s0012162201002493. View

4.
Corbett E, Watt C, Walker N, Maher D, Williams B, Raviglione M . The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch Intern Med. 2003; 163(9):1009-21. DOI: 10.1001/archinte.163.9.1009. View

5.
Thwaites G, Chau T, Farrar J . Improving the bacteriological diagnosis of tuberculous meningitis. J Clin Microbiol. 2004; 42(1):378-9. PMC: 321694. DOI: 10.1128/JCM.42.1.378-379.2004. View