Beta-carotene Therapy for Erythropoietic Protoporphyria and Other Photosensitivity Diseases

Overview

Journal Biochimie

Specialty Biochemistry

Date 1986 Jun 1

PMID 3092881

Citations 7

Affiliations

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Abstract

This paper describes the development of the use of carotenoid pigments in the treatment of light-sensitive skin diseases. It also discusses the animal and human studies involved in determining whether carotenoids have any anti-cancer activity. The possible mechanisms of carotenoid photoprotective and anti-cancer actions are briefly discussed.

Citing Articles

Successful treatment of severe hepatic impairment in erythropoietic protoporphyria: A case report and review of literature.

Zeng T, Chen S, Liu H, Chong Y, Li X World J Hepatol. 2024; 16(6):966-972.

PMID: 38948434 PMC: 11212650. DOI: 10.4254/wjh.v16.i6.966.

β-Carotene enhances the expression of inflammation-related genes and histone H3 K9 acetylation, K4 dimethylation, and K36 trimethylation around these genes in juvenile macrophage-like THP-1 cells.

Kondo S, Suzuki R, Nakashima Y, Mochizuki K Biochem Biophys Rep. 2022; 31:101325.

PMID: 35990579 PMC: 9388881. DOI: 10.1016/j.bbrep.2022.101325.

Nutrients and Porphyria: An Intriguing Crosstalk.

Pierro E, Granata F Int J Mol Sci. 2020; 21(10).

PMID: 32422947 PMC: 7279006. DOI: 10.3390/ijms21103462.

Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase.

Kim S, Lee S, Tak J, Choi K, Kwon T, Park J Mol Cell Biochem. 2007; 302(1-2):27-34.

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Method for the determination of beta-carotene in supplements and raw materials by reversed-phase liquid chromatography: single laboratory validation.

Schierle J, Pietsch B, Ceresa A, Fizet C, Waysek E J AOAC Int. 2004; 87(5):1070-82.

PMID: 15493663 PMC: 2586117.