Positive Culture Rate and Antimicrobial Susceptibilities of and

Overview

Journal Obstet Gynecol Sci

Specialty Gynecology & Obstetrics

Date 2019 Mar 29

PMID 30918881

Citations 9

Authors

Young-Soo Jang

Ji-Won Min

Yun-Sook Kim

Affiliations

Soon will be listed here.

Abstract

Objective: To assess positive culture rate and antimicrobial susceptibilities of (MH) and (UU) in symptomatic general population and pregnant women admitted with preterm labor and premature rupture of membranes.

Methods: We retrospectively reviewed medical records of patients who have undergone culture test and antimicrobial susceptibilities at our center from January 2017 to April 2018. Patients with positive culture for MH, UU, or both were included in this study.

Results: There were 200 patients who were eligible for enrollment. Of these patients, 34 (17%) were pregnant women and 166 (83%) were non-pregnant women. Of these 200 patients, positive culture results were as follows: MH only, n=10 (5%); UU only, n=58 (29%); and both MH and UU, n=36 (18%). Susceptibilities of MH only to doxycycline, erythromycin, ciprofloxacin, and azithromycin were 100%, 10%, 40%, and 0%, respectively. Susceptibilities of UU only to doxycycline, erythromycin, ciprofloxacin, and azithromycin were 94.8%, 87.9%, 5.2%, and 81%, respectively. Susceptibilities of both MH and UU to doxycycline, erythromycin, ciprofloxacin, and azithromycin were 97.2%, 5.6%, 11.1%, and 11.1%, respectively.

Conclusion: UU only was the leading causative pathogen for genitourinary infection in our study. MH only accounted for about one sixth of UU only infections. Doxycycline was still the best antibiotics as most patients with MH only, UU only, or both MH and UU positive culture showed susceptibility. For ciprofloxacin, less than 12% of those with UU only and both MH and UU culture positive results showed susceptibility.

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