Neuropathic Pain Screening: Construct Validity in Patients With Sickle Cell Disease

Overview

Journal West J Nurs Res

Publisher Sage Publications

Specialty Nursing

Date 2019 Mar 23

PMID 30900520

Citations 8

Authors

Keesha Powell-Roach

Yingwei Yao

Miriam O Ezenwa

Judith M Schlaeger

Marie L Suarez

Robert E Molokie

Zaijie Jim Wang

Diana J Wilkie

Affiliations

Soon will be listed here.

Abstract

Individuals with pain from sickle cell disease (SCD) are often treated for nociceptive pain, but recent findings indicate they may also have neuropathic pain. PAINIt, a computerized version of the McGill Pain Questionnaire, provides a potential subscale that is the summed number of selected neuropathic pain quality words (PR-NNP), but it lacks construct validity. The study purpose was to ascertain PR-NNP construct validity in adults with SCD and chronic pain. In an outpatient setting, 186 participants completed the PAINIt, Neuropathic Pain Symptom Inventory (NPSI), and Leeds Assessment for Neuropathic Symptoms and Signs (S-LANSS). PR-NNP was moderately correlated with NPSI ( = .33, < .001) and S-LANSS ( = .40, < .001). Regression analysis indicated that PR-NNP and pain intensity, but not a nociceptive pain subscale, were significant predictors of NPSI and S-LANSS. Findings support construct validity of PR-NNP, which may be useful as a screening tool for neuropathic pain in patients with SCD.

Citing Articles

Analysis of , thermal and pressure pain thresholds, and stress in sickle cell disease.

Powell-Roach K, Yao Y, Cao X, Chamala S, Wallace M, Cruz-Almeida Y Front Pain Res (Lausanne). 2023; 3:1060245.

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A Novel Measure of Pain Location in Adults with Sickle Cell Disease.

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A Stress and Pain Self-management mHealth App for Adult Outpatients With Sickle Cell Disease: Protocol for a Randomized Controlled Study.

Ezenwa M, Yao Y, Mandernach M, Fedele D, Lucero R, Corless I JMIR Res Protoc. 2022; 11(7):e33818.

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Prevalence of neuropathic pain in adolescents with sickle cell disease: A single-center experience.

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Kim J, Wilkie D, Weaver M, Lyon D, Kelly D, Millan S Adv Wound Care (New Rochelle). 2021; 10(10):544-556.

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