Impact of Spider Nevus and Subcutaneous Collateral Vessel of Chest/abdominal Wall on Outcomes of Liver Cirrhosis

Overview

Journal Arch Med Sci

Specialty General Medicine

Date 2019 Mar 23

PMID 30899297

Citations 6

Authors

Hongyu Li

Ran Wang

Nahum Mendez-Sanchez

Ying Peng

Xiaozhong Guo

Xingshun Qi

Affiliations

Soon will be listed here.

Abstract

Introduction: Spider nevus and subcutaneous collateral vessel of the chest/abdominal wall are common in liver cirrhosis. This prospective study aimed to evaluate the impact of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall on the outcomes of cirrhotic patients.

Material And Methods: We prospectively enrolled patients with a diagnosis of liver cirrhosis consecutively admitted to our department. We recorded the number and location of spider nevi and subcutaneous collateral vessels of the chest/abdominal wall. Clinical profiles and survival were compared according to the presence of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall. The study was registered (NCT02468479).

Results: Overall, 198 patients were enrolled between June 2015 and May 2016. The median follow-up duration was 350 days. The prevalence of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall was 47% and 29.8%, respectively. Patients with spider nevi had a significantly higher proportion of alcohol abuse (54.84% vs. 26.67%, < 0.001). Both spider nevus and subcutaneous collateral vessel of the chest/abdominal wall were significantly associated with higher Child-Pugh (8.35 ±2.19 vs. 7.47 ±1.91, = 0.005; 8.57 ±2.20 vs. 7.60 ±1.98, = 0.002) and MELD scores (9.91 ±6.41 vs. 7.43 ±5.40, = 0.008; 10.77 ±6.76 vs. 7.68 ±5.42, = 0.003). The cumulative survival was not significantly different between patients with and without spider nevi of the chest/abdominal wall ( = 0.951). Patients with subcutaneous collateral vessels of the chest/abdominal wall had significantly worse cumulative survival ( = 0.018).

Conclusions: Presence of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall indicated more severe liver dysfunction. Subcutaneous collateral vessel of the chest/abdominal wall should be a simple and important predictor for the overall survival of cirrhotic patients.

Citing Articles

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Computed Tomography Images of Spontaneous Portosystemic Shunt in Liver Cirrhosis.

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