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Laparoscopic Extirpation of Adrenal Gland Ganglioneuroma Incidentally Diagnosed During Evaluation for Patchy Alopecia Areata in an Adolescent Boy

Overview
Journal Med Princ Pract
Publisher Karger
Date 2019 Mar 22
PMID 30897574
Citations 1
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Abstract

Objective: We present a 17-year-old boy with an incidentally diagnosed left adrenal ganglioneuroma during the diagnostic workup of alopecia areata.

Clinical Presentation And Intervention: Laboratory investigations revealed vitamin D deficiency. Laparoscopic adrenalectomy was performed and ganglioneuroma was confirmed histologically. At follow-up, the vitamin D supplements improved the vitamin D levels followed by a gradual regression of alopecia areata. However, it recurred 18 months later despite the normal levels of serum vitamin D and no tumor recurrence.

Conclusion: Further studies should reveal the relationship between alopecia areata and ganglioneuroma as well as the role of vitamin D in alopecia areata.

Citing Articles

Adrenal ganglioneuroma: Prognostic factors (Review).

Sandru F, Dumitrascu M, Petca A, Carsote M, Petca R, Oproiu A Exp Ther Med. 2021; 22(5):1338.

PMID: 34630692 PMC: 8495554. DOI: 10.3892/etm.2021.10773.

References
1.
Zhou Y, Liang Q, Ou W, Li Z, Liu Q . Laparoscopic resection of primary adrenal ganglioneuroma: A case report and review of the literature. Oncol Lett. 2015; 9(5):2167-2170. PMC: 4467355. DOI: 10.3892/ol.2015.3021. View

2.
Spinelli C, Rossi L, Barbetta A, Ugolini C, Strambi S . Incidental ganglioneuromas: a presentation of 14 surgical cases and literature review. J Endocrinol Invest. 2014; 38(5):547-54. DOI: 10.1007/s40618-014-0226-y. View

3.
Chen C, Chang Y, Liu H, Chen Y . Cancer risk in patients with alopecia areata: a nationwide population-based matched cohort study. Cancer Med. 2018; 7(5):2153-2159. PMC: 5943418. DOI: 10.1002/cam4.1448. View

4.
Geraci A, de Csepel J, Shlasko E, Wallace S . Ganglioneuroblastoma and ganglioneuroma in association with neurofibromatosis type I: report of three cases. J Child Neurol. 1998; 13(7):356-8. DOI: 10.1177/088307389801300712. View

5.
Lora M, Waguespack S, Moley J, Walvoord E . Adrenal ganglioneuromas in children with multiple endocrine neoplasia type 2: a report of two cases. J Clin Endocrinol Metab. 2005; 90(7):4383-7. DOI: 10.1210/jc.2004-2526. View