Nicotine is a Risk Factor for Dental Caries: An Study

Overview

Journal J Dent Sci

Specialty Dentistry

Date 2019 Mar 22

PMID 30895091

Citations 17

Authors

Shiyu Liu

Tianmu Wu

Xuedong Zhou

Bo Zhang

Sibei Huo

Yutao Yang

Keke Zhang

Lei Cheng

Xin Xu

Mingyun Li

Affiliations

Soon will be listed here.

Abstract

Background/purpose: is an important pathogen in the development of dental caries. Many studies have focused on the relationship between nicotine and . The aim of this study was to investigate the effect of nicotine on the growth of and its cariogenic potential .

Materials And Methods: Sixteen male Specific-pathogen-free Wistar rats were divided into 2 groups (nicotine-treated and nicotine-untreated group) and infected with . The suspension was treated with 1 mg/mL nicotine in the nicotine-treated group. The Keyes method was used to evaluate sulcal caries of rats, and dental plaque on molar teeth was observed by scanning electron microscopy (SEM).

Results: Incidence of sulcal caries was higher in nicotine-treated group compared to nicotine-untreated group (42.7 ± 1.7 vs 37.3 ± 4.9, P = 0.009). Severity of caries increased with nicotine treatment. The slightly dentinal caries scores and moderate dentinal caries scores were higher in the presence of nicotine (P < 0.001). Increased number of cells attached to dental surface was observed under SEM in the nicotine-treated group.

Conclusion: Nicotine would promote the attachment of to dental surface, and further increase the incidence and severity of dental caries. Therefore, nicotine might be a risk factor for smoking-induced caries.

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