Meal for Two: Human Cytomegalovirus-Induced Activation of Cellular Metabolism

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2019 Mar 22

PMID 30893762

Citations 27

Authors

Irene Rodriguez-Sanchez

Joshua Munger

Affiliations

Soon will be listed here.

Abstract

Viruses are parasites that depend on the host cell's metabolic resources to provide the energy and molecular building blocks necessary for the production of viral progeny. It has become increasingly clear that viruses extensively modulate the cellular metabolic network to support productive infection. Here, we review the numerous ways through which human cytomegalovirus (HCMV) modulates cellular metabolism, highlighting known mechanisms of HCMV-mediated metabolic manipulation and identifying key outstanding questions that remain to be addressed.

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