» Articles » PMID: 30886527

Peritoneal Dialysis and Malignancy: An Experience With a Patient Complicated by Gastric Carcinoma

Overview
Publisher Sage Publications
Specialty General Medicine
Date 2019 Mar 20
PMID 30886527
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

An 86-year-old man who had been treated with peritoneal dialysis for 14°months due to end-stage kidney disease secondary to hypertensive nephrosclerosis presented with a recent history of malaise, abdominal discomfort, and anorexia. An endoscopic evaluation revealed an elevated, ulcerated, and friable lesion around the lesser curvature of the stomach. The concurrent gastric biopsy specimens revealed moderately differentiated adenocarcinoma, while a cytological examination of the dialysis fluid revealed clusters of malignant cells. This is the first report illustrating a case of a Borrmann type 3 gastric cancer with synchronous peritoneal involvement in which the assessment of the disease state was aided by the cytological analysis of peritoneal effluent. Several concerns relating to this pathology are also discussed.

Citing Articles

Knockdown of ST7-AS1 inhibits migration, invasion, cell cycle progression and induces apoptosis of gastric cancer.

Cai S, Weng Y, Liu P, Miao F Oncol Lett. 2020; 19(1):777-782.

PMID: 31897194 PMC: 6924146. DOI: 10.3892/ol.2019.11145.

References
1.
Maisonneuve P, Agodoa L, Gellert R, Stewart J, Buccianti G, Lowenfels A . Cancer in patients on dialysis for end-stage renal disease: an international collaborative study. Lancet. 1999; 354(9173):93-9. DOI: 10.1016/s0140-6736(99)06154-1. View

2.
Teitelbaum I . Cloudy peritoneal dialysate: it's not always infection. Contrib Nephrol. 2006; 150:187-194. DOI: 10.1159/000093594. View

3.
Shimizu H, Ishibashi Y, Kumagai T, Kawarazaki H, Kawarazaki W, Kaname S . Successful reinstitution of peritoneal dialysis after gastric resection: a case report. Perit Dial Int. 2006; 26(4):509-10. View

4.
Vlahakos D, Rudders R, Simon G, Canzanello V . Lymphoma-mimicking peritonitis in a patient on continuous ambulatory peritoneal dialysis (CAPD). Perit Dial Int. 1990; 10(2):165-7. View

5.
Abbasi S, Taani H, Saad A, Badheeb A, Addasi A . Advanced gastric cancer in jordan from 2004 to 2008: a study of epidemiology and outcomes. Gastrointest Cancer Res. 2012; 4(4):122-7. PMC: 3283110. View