» Articles » PMID: 30882710

Associations of Plasma LP(a), Hcy and D-D Levels with the Subtype of Ischemic Cerebrovascular Disease

Overview
Specialty General Medicine
Date 2019 Mar 19
PMID 30882710
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

The relevance of LP(a), Hcy, and D-D in ischemic cerebrovascular disease remains undefined. This study aimed to assess the associations of plasma LP(a), Hcy and D-D levels with the subtype of ischemic cerebrovascular disease.Patients with ischemic cerebrovascular disease admitted to the Taixing People's Hospital were retrospectively enrolled from November 2017 to July 2018. Immunoturbidimetry was used to assess 119 LAA, 107 SAO, and 112 TIA patients for plasma LP(a), Hcy, and D-D levels.Plasma LP(a), Hcy, and D-D levels in the large artery atherosclerosis (LAA) group were significantly lower than those of the transient ischemic attack (TIA) group (all P < .05). LP(a), Hcy, and D-D levels were significantly reduced in the SAO group compared with the TIA group (both P < .05). The LAA and SAO groups showed comparable values for all the above parameters (P > .05).LP(a), Hcy, and D-D levels differ according to the subtype of ischemic cerebrovascular disease.

Citing Articles

Lipoprotein (a) level as a risk factor for stroke and its subtype: A systematic review and meta-analysis.

Kumar P, Swarnkar P, Misra S, Nath M Sci Rep. 2021; 11(1):15660.

PMID: 34341405 PMC: 8329213. DOI: 10.1038/s41598-021-95141-0.


Homocysteine: Its Possible Emerging Role in At-Risk Population Groups.

Azzini E, Ruggeri S, Polito A Int J Mol Sci. 2020; 21(4).

PMID: 32093165 PMC: 7073042. DOI: 10.3390/ijms21041421.

References
1.
Huang S, Yin L, Xu Y, Zou C, Chen L . The homocysteine associated variant rs548987 of SLC17A3 confers susceptibility to ischemic stroke in Chinese population. J Neurol Sci. 2016; 370:78-81. DOI: 10.1016/j.jns.2016.08.037. View

2.
Anniwaer J, Liu M, Xue K, Maimaiti A, Xiamixiding A . Homocysteine might increase the risk of recurrence in patients presenting with primary cerebral infarction. Int J Neurosci. 2018; 129(7):654-659. DOI: 10.1080/00207454.2018.1517762. View

3.
Ariens R . Elevated fibrinogen causes thrombosis. Blood. 2011; 117(18):4687-8. DOI: 10.1182/blood-2011-03-340422. View

4.
Wang G, Cheng X, Zhang X . Use of various CT imaging methods for diagnosis of acute ischemic cerebrovascular disease. Neural Regen Res. 2014; 8(7):655-61. PMC: 4145983. DOI: 10.3969/j.issn.1673-5374.2013.07.010. View

5.
Tan S, Zhang L, Chen X, Wang Y, Lin Y, Cai W . Comparison of the Chinese ischemic stroke subclassification and Trial of Org 10172 in acute stroke treatment systems in minor stroke. BMC Neurol. 2016; 16(1):162. PMC: 5011990. DOI: 10.1186/s12883-016-0688-y. View