Combination of Clindamycin and Azithromycin As Alternative Treatment for Toxoplasma Gondii Encephalitis
Overview
Affiliations
Current standard therapies for toxoplasmic encephalitis often cause severe adverse events. A 57-year-old HIV-positive man in Japan who had toxoplasmic encephalitis but was intolerant to trimethoprim/sulfamethoxazole, pyrimethamine, sulfadiazine, and atovaquone was successfully treated with the combination of clindamycin and azithromycin. This drug combination can be an alternative treatment for this condition.
Moon M, Kamasah J, Sharma H, Robertson B, Abugri D Front Cell Infect Microbiol. 2024; 14:1368019.
PMID: 39588510 PMC: 11586383. DOI: 10.3389/fcimb.2024.1368019.
Ramos M, Villaraza S Encephalitis. 2023; 3(2):64-70.
PMID: 37469675 PMC: 10295825. DOI: 10.47936/encephalitis.2022.00115.
Anti-Toxoplasma gondii activity of Trametes versicolor (Turkey tail) mushroom extract.
Sharma H, Catrett J, Nwokeocha O, Boersma M, Miller M, Napier A Sci Rep. 2023; 13(1):8667.
PMID: 37248277 PMC: 10225767. DOI: 10.1038/s41598-023-35676-6.
A Metabolomic and Transcriptomic Study Revealed the Mechanisms of Lumefantrine Inhibition of .
Li M, Sang X, Zhang X, Li X, Feng Y, Yang N Int J Mol Sci. 2023; 24(5).
PMID: 36902335 PMC: 10003460. DOI: 10.3390/ijms24054902.
Yuan H, Zhang X, Yang Z, Wang X, Mahmmod Y, Zhang P Parasit Vectors. 2022; 15(1):263.
PMID: 35871661 PMC: 9308931. DOI: 10.1186/s13071-022-05378-5.